Download RGUHS Pharm-D 1st Semester 2011 Feb 2855 Pharmaceutical Inorganic Chemistry Question Paper

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Rajiv Gandhi University of Health Sciences, Karnataka

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First Year Pharma-D Examination - Feb/March 2011

Time: Three Hours

Max. Marks: 70 Marks

PHARMACEUTICAL INORGANIC CHEMISTRY

Q.P. CODE: 2855

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Your answers should be specific to the questions asked

Draw neat labeled diagrams wherever necessary

LONG ESSAYS (Answer any Two) 2 x 10 = 20 Marks

1. Discuss the sources of impurities in pharmaceuticals with examples. How do impurities affect the quality of pharmaceutical substances
2. Describe the principle involved in the Mohr's and Volhard's method for the determination of chlorides. Explain the mechanism of indicators in the determination of the end point in Fajan's method with examples

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3. Explain the principle and reactions involved in the assay of ferrous sulphate and sodium benzoate

SHORT ESSAYS (Answer any Six) 6 x 5 = 30 Marks

4. Write the principle involved in limit test for iron
5. What are antacids? Classify them with examples. Write the method of preparation of aluminium hydroxide gel.
6. Give a brief account of oral rehydration salts and their formulations

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7. What are antidotes? Outline the role of activated charcoal in poisoning
8. Give the method of preparation and uses of nitrous oxide as medicinal gas
9. What are anticaries agents? Write the method of preparation and uses of sodium fluoride
10. Differentiate between iodometry and iodimetry

SHORT ANSWERS 10 x 2 = 20 Marks

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12. What is back titration? Explain the principle involved in the assay of copper sulphate.
13. How do you prepare 100 ml of 0.1 N sodium hydroxide volumetric solution?
14. Write the storage condition of potassium permanganate volumetric solution
15. Why is dilute nitric acid used in the limit test for chlorides?
16. What is a self indicator?

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17. What are saline cathartics? Give examples
18. Write the reaction involved in the assay of hydrogen peroxide
19. What are astringents? Give examples
20. What is the importance of calcium in human nutrition?
21. Complete the following reactions and balance them if necessary:
    1. AgNO₃ + NH₄SCN ?

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    2. I₂ + Na₂S₂O₃ ?

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