First Year MBBS Examination
I MBBS PHYSIOLOGY PAPER II
Date: 04-02-2021
Time: 3 hours Max Marks: 100
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Instructions: INSTRUCTIONS: Attempt allquestions in both sections: (Use separate
answer book for each section)
Section 1
1. Fill in the blanks:: 6x1=06
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a. Cyanide poisoning is an example ofhypoxia.
b. Cholelithiasis is presence of stones in
c. Heart rate increases during inspiration
and decreases during expiration. This
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is calledd. The site of erythropoiesis in the adult
is
e. are called are exchange vessels.
f. Inability of the kidney to respond to
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ADH results in2. Choose the correct option in the following
multiple choice questions:
a. A person complains of passing clay
colored, bulky, greasy and foul
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smelling faeces for last two three days,most likely he is having : a)
Malabsorption syndrome b) Pancreatic
insufficiency c) Hepatitis d)
Obstruction of bile ducts
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b. Pulmonary function changes seen inemphysema are: a) Increased TLC b)
Decreased RV c) Increased FEV1 d)
Increased VC
c. Which if the following is the principle
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buffer in interstitial fluid? a)Hemoglobin b) Other proteins c)
Carbonic acid d) H2PO4
d. Which of the following components of
the circulatory system contains the
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largest percentage of the total bloodvolume? a) Arteries b) Capillaries c)
Veins d) Heart
3. A 40-year old woman visits the clinic
complaining of fatigue. She had recently
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been treated an infection. Her laboratoryfindings are as follows: RBC count - 1.8
millions/cc; Hemoglobin 5.2 gm/dL;
Haematocrit-15 WBC count-7600/cc:
Platelet count-320000/cc: MCV-92 fl,
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Reticulocyte count-24%. Based on theabove case scenario, answer the following
questions- a) What is the most likely
diagnosis for this condition? b) What is the
pathophysiology of the disease diagnosed?
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c) Give etiological and morphologicalclassification of the condition diagnosed.
4. Write short notes on (any five): 5x2=10
a. PR interval
b. Law of Laplace
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c. Obstructive jaundiced. Segmentation contraction
e. Lung compliance
f. Vitamin K antagonists
5. Explain briefly (any two): 3x5=15
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a. Timed vital capacity and itsimportance
b. Respiratory changes during muscular
exercise
c. Rennin Angiotensin system (A.634)
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(B.261) (C1-733)d. Regulation of exocrine pancreatic
secretion
Section 2
1. Define and classify hypoxia. Give examples
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of cach type. Mention distinguishingfeatures of each type of hypoxia. Explain
the role of oxygen treatment in different
types of hypoxia. Add a note on oxygen
toxicity.
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2. Explain why(Any five)a. Heart rate increases in linearity with
severity of exercise
b. Alveoli remain dry.
c. Para Aminohippuric acid clearance is
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used for the measurement of renalblood flow.
d. Vitamin K antagonists are used as
anticoagulants.
e. Proton pump inhibitors are used
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clinically for the treatment of gastriculcers of various aetiologies.
f. There is a post prandial alkaline tide
3. Explain briefly (any four): 4x5=20
a. Autoimmunity
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b. Work of breathingc. Renal mechanisms of maintenance of
normal specific gravity of urine
d. Physiological effects of physical
training
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e. Hemoglobinopathiesf. Transport maximum for glucose (C1-
529)
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