RUHS
First Year MBBS Examination
I MBBS PHYSIOLOGY PAPER I
Date: 02-02-2021
Time: 3 hours

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Max Marks: 100
Instructions: INSTRUCTIONS: Attempt all
questions in both sections: (Use separate
answer book for each section)
Section 1

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1. Fill in the blanks: (6)
a. In ________ the muscle weakness is
caused by an autoimmune attack against
one of the CA2+ channels in the nerve
endings at the neuromuscular junction.

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b. The deep reflexes become weak in
pendular in _________ lesion.
c. High circulating levels of progesterone and
estrogens in pregnancy prevent _______

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bleeding and cause amenorrhea.

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d. Cushing's disease is due to excessive
levels of ________ .
e. Visual receptors not found at ________
part of the eye.
f. Glucose enters in the intestine and renal

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tubules by ________ transport.
2. Choose the correct option in the following
multiple choice questions: (4)
a. Flocculonodunar lobe is directly connected
to; a) Vestibular nucleus b) Red nucleus c)

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Dentate nucleus d) Inferior olivary nucleus
b. Capacitation of sperm takes place in- a)
Seminiferous tubules b) Epididymis c) Vas
deferens d) Uterus
c. Which of the following best describes a

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physiological difference between the
contraction of smooth muscle compared
with the contraction of cardiac muscle and
skeletal muscle? a) Ca+2 independent b)
Does not require any action potential c)

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Requires more energy d) Shorter in
duration
d. Neurotransmitter released at sympathetic
preganglionic fibres- a) Epinephrine b) Nor
epinephrine c) Acetyl choline d) Dopamine

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3. A 45 year old man visits a physician because
of difficulties performing simple tasks that
involve repetitive movements. The physician
asks to turn one hand upward and downward
at a rapid pace the man quickly loses all

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perception of the instantaneous position of
the hand, which results in a series of delayed
attempts and jumbled movements. Use this
information to answer the following
questions; (15)

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a. This patient's neurological signs are most
likely related to lesion within which part of
the brain ?name the probable condition
with its pathophysiology.
b. What are the connections and the

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functions of this part of the brain?
c. What are the other characteristics of
disease associated with dysfunction of this
part.
4. Write short notes on (any five): 5x2=10 (10)

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a. Dark adaptation (C2- 1109)
b. Decerebrate rigidity (C2-955)

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c. Thalamic syndrome
d. Sarcotubular system
e. Impedance matching

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f. Passive transport
5. Explain briefly (any three): 3x5=15 (15)
a. Endogenous pain relief system
b. Female contraceptives
c. Stretch reflex

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d. Compositions and functions of
cerebrospinal fluid (C1-373)
Section 2
1. Discuss the common causes of infertility in a
couple and role of in-vitro fertilization in

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managing a case of infertility, describe the
following changes during different phases of
menstrual cycle along with a suitable
diagram; (20)
a. Hormonal

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b. Uterine
c. Ovarian
d. Vaginal
2. What will happen and why (Any fivc):: 5x2-10

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2. What will happen and why (Any fivc):: 5x2-10

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(10)
a. If circulating levels of free Thyroxin &
Triiodothyronine decrease in infants.
b. If LH surge rge in an ovulatory cycle is
absent

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c. If vascular blockage of the thalamus
occurs
d. If Ciliary muscles get temporary paralyzed
e. To pupil in oculomotor nerve paralysis
f. To menstrual cycle in breast-feeding lady

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3. Explain briefly (Any four): 4x5=20 (20)
a. Suckling reflex (C2-682)
b. Mechanism of accommodation of
Eye(A.995) (8.894) (C2-1103)
c. Functions of insulin

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d. Differentiate between action potential and
receptor potential
e. Tests of pregnancy
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