Pharm D Last 12 Years 2010-2022 Question Papers (1st Year, 2nd Year, 3rd Year, 4th Year and 5th Year)
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[LB 817] OCTOBER 2012 Sub. Code: 3817
DOCTOR OF PHARMACY (PHARM. D) DEGREE EXAMINATION
THIRD YEAR
PAPER V - MEDICINAL CHEMISTRY
O.P. Code: 383817
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Time: Three Hours Maximum: 100 marks
Answer ALL questions in the same order
I. Elaborate on : Pages Time Marks
(Max.) (Max.) (Max.)
- Write the classification of Antineoplastic agents and explain in detail their chemistry with suitable examples along with mechanism of action. Synthesize any two drugs under various classes. 17 40 min. 20
- Classify cardiovascular agents. Discuss on antihypertensives and antiarrythmics in detail. 17 40 min. 20
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II. Write notes on:
- Brief out on prodrugs and their applications. 4 10min. 6
- Write on thiazides and osmotic diuretics. 4 10min. 6
- Give a short account on anti thyroid hormones. 4 10min. 6
- Write on the electronic, lipophilic and steric parameters. 4 10min. 6
- What is the concept of antisense molecules? 4 10min. 6
- Discuss on macrolides. 4 10min. 6
- Write the chemistry, structures and synthesis of any one drug under the category of anthelmintics. 4 10min. 6
- Discuss on oral hypoglycemic agents. 4 10min. 6
- Brief out on computer aided drug design. 4 10min. 6
- Classify broad spectrum pencillins and write the mechanism of action. 4 10min. 6
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