[LD 814] OCTOBER 2013 Sub. Code: 3814
DOCTOR OF PHARMACY (PHARM. D) DEGREE EXAMINATION
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THIRD YEAR
PAPER II - PHARMACEUTICAL ANALYSIS
Q.P. Code: 383814
Time: Three Hours Maximum: 70 marks
Answer All questions
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- Elaborate on: (2x20=40)
- Explain the different electronic transitions involved in UV spectrophotometry with examples.
- Describe the theory and instrumentation of DSC.
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- Explain the principle and instrumentation of IR spectroscopy with a neat diagram.
- Describe the theory and instrumentation of atomic absorption spectrometry.
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II. Write notes on: (10x 3 =30)
- Write a brief note on theoretical aspects of mass spectra.
- Give a brief account on ICH guidelines.
- What is ion-exchange chromatography? List the different types of ion exchange resins used in ion-exchange chromatography.
- List the detectors used in GLC. Explain the principle of any one.
- What is plane polarized light? Define optical rotatory dispersion and circular dichroism.
- Explain any three factors affecting the fluorescence intensity.
- Explain the working principle of hydrogen electrode with a neat diagram.
- Write a brief note on conductometric titrations.
- Write a note on chemical shift.
- Explain briefly the applications of flame photometry.
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