Pharm D Last 12 Years 2010-2022 Question Papers (1st Year, 2nd Year, 3rd Year, 4th Year and 5th Year)
[LD 817] OCTOBER 2013 Sub. Code: 3817
DOCTOR OF PHARMACY (PHARM. D) DEGREE EXAMINATION
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THIRD YEAR
PAPER V - MEDICINAL CHEMISTRY
Q.P. Code: 383817
Time: Three Hours Maximum: 70 marks
Answer All questions
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- Elaborate on: (2x20=40)
- What are Tetracyclines and Classify with structural examples for each? Discuss briefly SAR, Chemistry and mechanism action of Tetracyclines.
- a) Classify antitubercular agents.
b) Give synthesis of any two drugs with mechanism of action.
c) Explain briefly antiprotozoal agents.
- Write notes on: (10x 3 =30)
- What is prodrug? Explain the types of pro drugs with suitable examples
- Give a method of synthesis of:
(i) Hexachlorphene (ii) Halazone - Classify anti fungal agents and give their mechanism of action
- What are urinary tract anti-infectives? Classify them with suitable examples
- Give the structure and uses of
(i) INH (ii) Ethionamide (iii) Pyrazinamide - Explain the mechanism of action of Metronidazole
- Write a short note on HIV protease inhibitors
- What is Crystalluria? How can it be prevented?
- Explain the life cycle of malarial parasite
- Write short notes on polypeptide antibiotics.
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