Download Pharm D 3rd Year 2014 October 383817 Medicinal Chemistry Question Paper

Download Pharm-D (Doctor of Pharmacy) 3rd Year (Third Year) 2014 October 383817 Medicinal Chemistry Previous Question Paper || pharm d question paper-pharm d 3rd year previous question papers ou-pharm d question bank-pharm d 3rd year previous question papers ku-pharm d previous question papers jntuh-pharm d question papers rguhs-mgr university pharm d question paper-pharm d third year previous question papers jntuh

[LF 817] OCTOBER 2014 Sub. Code: 3817

DOCTOR OF PHARMACY (PHARM. D) DEGREE EXAMINATION

(2009-2010 Regulation)

THIRD YEAR

PAPER V ? MEDICINAL CHEMISTRY

Q.P. Code: 383817

Time: Three Hours











Maximum: 70 marks

Answer All questions

I. Elaborate on:

















(4 x 10 = 40)

1. Explain the medicinal chemistry aspects of antihypertensive agents with emphasis to

classification and mechanism of action of each class.

2. Enumerate various approaches utilized in computer aided drug design.

3. Discuss the chemistry, mechanism of action, SAR and synthesis of chloramphenicol.

4. Write a note on urinary tract anti-infectives and enumerate the synthesis of any one.

II. Write notes on:











(6 x 5 = 30)

1. Write a note on antimetabolites used in anticancer therapy.

2. Classify oral hypoglycaemic agents and enumerate the synthesis of any one.

3. Discuss the structural types of quinolone urinary tract anti-infectives and write the

structure any one flouro quinolone.

4. Write a note on estrogens and non steroidal estrogens.

5. Explain briefly on lipophilic parameters in quantitative structure activity relationship.

6. Give the structure and uses of

(a) Acetazolamide

(b) Pyrimethamine



*******