Pharm D Last 12 Years 2010-2022 Question Papers (1st Year, 2nd Year, 3rd Year, 4th Year and 5th Year)
[LF 817] OCTOBER 2014 Sub. Code: 3817
DOCTOR OF PHARMACY (PHARM. D) DEGREE EXAMINATION
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(2009-2010 Regulation)
THIRD YEAR
PAPER V — MEDICINAL CHEMISTRY
Q.P. Code: 383817
Time: Three Hours Maximum: 70 marks
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Answer All questions
- Elaborate on: (4 x10=40)
- Explain the medicinal chemistry aspects of antihypertensive agents with emphasis to classification and mechanism of action of each class.
- Enumerate various approaches utilized in computer aided drug design.
- Discuss the chemistry, mechanism of action, SAR and synthesis of chloramphenicol.
- Write a note on urinary tract anti-infectives and enumerate the synthesis of any one.
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- Write notes on: (6x5=30)
- Write a note on antimetabolites used in anticancer therapy.
- Classify oral hypoglycaemic agents and enumerate the synthesis of any one.
- Discuss the structural types of quinolone urinary tract anti-infectives and write the structure any one flouro quinolone.
- Write a note on estrogens and non steroidal estrogens.
- Explain briefly on lipophilic parameters in quantitative structure activity relationship.
- Give the structure and uses-of
- Acetazolamide
- Pyrimethamine
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