Sub. Code: 3817
(OCTOBER 2020 EXAM SESSION)
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PHARM. ‘D’ DEGREE EXAMINATION
THIRD YEAR (2009-2010 Regulation)
PAPER V — MEDICINAL CHEMISTRY
O.P. Code : 383817
Time : Three hours Maximum : 70 Marks
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- I. Elaborate on: (4 x 10 =40)
- Classify anti fungal agents. Explain in detail about the chemistry, mechanism of action and synthesis of any 2 drugs.
- Explain the Physicochemical properties involved in QSAR study.
- Define and classify anti TB drugs. Write the structure, mechanism of action and synthesis of any 2 drugs.
- Classify antibiotics. Discuss the chemistry of Penicillin.
- II. Write notes on: (6x5=30)
- Write notes on calcium channel blockers.
- Give structure and uses of chloroquine and metronidazole.
- Write notes on Antimetabolites as Anti neoplastic agents.
- SAR of quinolones.
- Write the synthesis of any 2 sulphonamides.
- Write notes on anti thyroid drugs.
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