11-MBBS
(This paper consists of 02 pages)
Second M.B.B.S. (Supp) Exam. (New
Scheme)
--- Content provided by FirstRanker.com ---
May-2025PHARMACOLOGY
Paper-11
Time: Three Hours Maximum Marks: 100
Attempt all questions in both sections
--- Content provided by FirstRanker.com ---
(Use separate answer book for each section)Section-A
Q.1 Fill in the blanks: (6x1 = 6 marks)
a. Gray baby syndrome is caused by
__________
--- Content provided by FirstRanker.com ---
b. Rifampicin is a potent inducer of__________enzyme.
c. HAART is used in the treatment of
__________
d. The antidote for digoxin poisoning is
--- Content provided by FirstRanker.com ---
__________e. __________ is antagonist of aldosterone.
f. Enalapril in liver is converted to __________
Q.2 Multiple Choice Questions (MCQ): (1-4
marks)
--- Content provided by FirstRanker.com ---
1. Which drug causes lactic acidosis as a rareadverse effect?
A. Glibenclamide
B. Metformin
C. Pioglitazone
--- Content provided by FirstRanker.com ---
D. Acarbose2. The most common adverse effect of
aminoglycosides is:
A. Hepatotoxicity
B. Hypoglycemia
--- Content provided by FirstRanker.com ---
C. NeutropeniaD. Ototoxicity
3. Which of these is NOT an adverse effect of
corticosteroids?
A. Hyperglycemia
--- Content provided by FirstRanker.com ---
B. HypotensionC. Osteoporosis
D. Immunosuppression
4. Which of the following is a potassium
retaining diuretics,
--- Content provided by FirstRanker.com ---
A. TriamtereneB. Trimethoprim
C. Tizanidine
D. Trimetazidine
Q.3 Clinical Case Study 15 marks
--- Content provided by FirstRanker.com ---
A 28-year-old female presents with complaintsof chronic dry cough, facial puffiness, and frothy
urine. Her blood pressure is 150/95 mmHg, and
urine shows significant proteinuria. She is
diagnosed with early diabetic nephropathy. She
--- Content provided by FirstRanker.com ---
is started on enalapril.Answer the following:
1. Classify ACE Inhibitors?
2. Mention the mechanism of action of enalapril.
3. What are common adverse effects of
--- Content provided by FirstRanker.com ---
enalapril?4. If the patient develops a persistent dry cough,
which alternative drug can be considered?
5. Enumerate therapeutic uses of enalapril.
Q.6 Write short notes on any FIVE of the
--- Content provided by FirstRanker.com ---
following. 5 x 2 = 10 marksa. Linezolid
b. Sulfonamide - mechanism of action
c. Insulin lispro
d. Radioactive iodine
--- Content provided by FirstRanker.com ---
e. Dimercaprol/
f. Dexamethasone
Q.7 Explain briefly - Any three 3 x 5 = 15
marks
a. Superinfection
--- Content provided by FirstRanker.com ---
b. Pharmacotherapy of leprosyc. Mechanism and adverse effects of
amphotericin B
d. Drug interactions of oral contraceptives and
rifampin
--- Content provided by FirstRanker.com ---
Section-BQ.6 Structured Essay Type Question with
Clinical Interpretation 20marks
Case: A 50-year-old female with poorly
controlled type 2 diabetes is started on insulin
--- Content provided by FirstRanker.com ---
glargine and metformin. After a few weeks sheexperiences hypoglycaemia and Glupset.
Answer the following:
a. Write the classification of antidiabetic drugs
b. Explain the mechanism of action of
--- Content provided by FirstRanker.com ---
metformin and insulin glargine.c. What precautions are taken while insulin
therapy?
d. Mention two symptoms of hypoglycaemia.
e. How is hypoglycaemia managed?
--- Content provided by FirstRanker.com ---
Write short notes on any FIVE 5 x 2 = 10marks
a. Antiseptics
b. HMG Co A inhibitors
c. Mechanism of action of nitrates
--- Content provided by FirstRanker.com ---
d. Alpha methyldopae. Anabolic steroids
f. Hypothalmo-Pitutary-Adrenal (HPA) axis
suppression
Explain briefly - ANY FOUR 4 x 5 = 20 marks
--- Content provided by FirstRanker.com ---
a. Dipeptidyl peptidase 4-inhibitors.b. Aromatase inhibitors
c. Methoterxate
d. Role of ACE inhibitors in CHF
e. Adenosine
--- Content provided by FirstRanker.com ---
***