Download RGUHS M.Pharm 1st Year 2020 5134 Advanced Pharmacology I Question Paper

SECTION I 3 X 10 = 30 Marks

1. Explain the molecular structure and signal transduction of G-protein coupled receptors through secondary messengers. FirstRanker.com
2. Classify anti-hypertensives with examples. Describe the pharmacotherapy of hypertension and write the mechanism of action of beta blockers.

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3. Explain the steps involved in neurohumoral transmission in the central nervous system. Add a note on any one neurotransmitter of the CNS.
4. Define and classify sedatives and hypnotics with examples. Write the pharmacology of Barbiturates.

SHORT ESSAY (Answer any Nine) 9 X 5 = 45 Marks

5. Plasma half-life and its significance.
6. Write the physiological and pathological role of kinins.

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7. Explain the extrapyramidal side effects of antipsychotic drugs.
8. Write the uses of anti-platelet drugs and give two examples.
9. Classify H1 blockers and write the uses and adverse effects of Ranitidine.
10. Explain the role of diuretics as antihypertensive therapy.
11. Discuss the mechanism of action of succinylcholine.

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12. Explain the physiological role of serotonin in the brain.
13. Write a note on drug-receptor interaction.
14. Write the uses and adverse effects of Phenytoin.