Download RGUHS (Rajiv Gandhi University of Health Sciences) M.Pharm (Master of Pharmacy) 1st Year (First Semester) 2020 5112 Advanced Pharmaceutical Analysis Previous Question Paper
First Semester M. Pharm Degree Examination - 20-Jan-2020
[Time: 3 Hours]
[Max. Marks: 75]
Advanced Pharmaceutical Analysis
Q.P. CODE: 5112
Your answers should be specific to the questions asked.
Draw neat, labeled diagrams wherever necessary.
LONG ESSAY (Answer any Three)
3 X 10 = 30 Marks
1.
Explain the principle and procedure involved in the assay of any one official drug each as per
IP for the following methods
a) Non-aqueous titrations b) potentiometric titrations
2.
Explain the principle and applications of the following reagents
a) Methyl -2 benzthiazolinone hydrazine(MBTH)
b) Para-dimethyl ?amino benzaldehyde (PDAB)
3.
Explain the the principle and procedure involved in quantitative estimation of drugs containing
following functional groups/Element.
a) Carboxyl group b) Halogen group
4.
Describe in detail the biological assay of Adsorbed Diphtheria vaccine.
SHORT ESSAY (Answer any Nine)
9 X 5 = 45 Marks
5.
Describe analysis of any one drug by RP-HPLC.
6.
Explain in brief analysis of any one drug by UV-extinction method.
7.
Explain the principle and applications of 2, 6 Dichloroquinone chlorimide in drug analysis?
8.
Write the procedure and applications of 1, 2 ? napthaquinone-4-sulfonate in drug analysis?
9.
Explain a method for determination of calcium.
10. Explain the principle and procedure of any one method for the estimation of Sodium.
11. Describe in brief biological assay of Oxytocin.
12. Write a brief note on biological assay of Heparin sodium IP.
13. Classify residual solvents and describe their permissible limits in drug products.
14. Write a brief note on potential sources of elemental impurities.
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This post was last modified on 27 March 2021