Download NTRUHS (DR. N.T.R UNIVERSITY OF HEALTH SCIENCES) MBBS (Bachelor of Medicine and Bachelor of Surgery) 2nd Year Pharmacology And Therapeutics Syllabus
SYLLABUS FOR 2nd PROFESSIONAL
4) PHARMACOLOGY & THERAPEUTICS
(i) Goal:
The broad goal of the teaching of undergraduate student in pharmacology is to inculate a
rational and scientific basis of therapeutics.
(ii) Objectives:
(a) KNOWLEDGE:
At the end of the course, the student shal be able to:
(1) Describe the pharmacokinetics and pharmacodynamics of essential and commonly used
drugs;
(2) List the Indications, contraindications, interactions and adverse reactions of commonly
used drugs;
(3) Indicate the use of appropriate drug in a particular disease with consideration to its cost,
efficacy and safety for
(i) Individual needs;
(i ) Mass therapy under national health programmes
(4) Describe the pharmacokinetic basis clinical presentation, diagnosis and management of
common poisonings;
(5) List the drugs of addition and recommend the management;
(6) Classify environmental and occupational pollutants and state the management issues;
(7) Indicate causations in prescription of drugs in special medical situations such as
pregnancy, lactation, infancy and old age;
(8) Integrate the concept of rational drug therapy in clinical pharmacology;
(9) State the principles underlying the concept of Essential Drugs;
(10) Evaluate the ethics and modalities involved in the development and introduction of new
drugs;
(b)
SKILLS:
At the end of the course, the student shal be able to:
(1)
Prescribe drugs for common ailments;
(2)
Recognise adverse reactions and interactions of commonly used drugs;
(3)
Observe experiments designed for study of effects of drugs, bioassay and
interpretation of the experimental date;
(4)
Scan information on common pharmaceutical preparations and critical y evaluate
drug formullations;
(c) INTEGRATION:
Practical knowledge of use of drugs in clinical practice will be acquired through integrated
teaching with clinical departments are pre clinical departments.
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4) SYLLABUS OF PHARMACOLOGY:
i) Theory
Sl.No.
Name of the Unit
No. of Hours
1.
General pharmacology
10
2.
Autonomic nervous system
8
3.
Central nervous system
16
4.
Cardio vascular system
8
5.
Biogenic amines & Autocoids
3
6.
Respiratory system
2
7.
Blood and blood forming agents
Anticoagulants, fibrinolytic drugs etc.,
4
8.
Kidney ? diuretics
2
9.
Gastro intestinal system
3
10.
Drugs acting on the Uterus
1
11.
Chemotherapy
22
12.
Endocrinology
10
13.
Dermatological Pharmacology
1
14.
Geriatric pharmacology
1
15.
Paediatric Pharmacology/Neonatal Pharmacology
1
16.
Safety of drugs in Pregnancy
1
17.
Hazards of smoking, alcohol, narcotics,
2
Environmental pollution
18.
Immuno Pharmacology
1
19.
Metal ic poisoning
1
20.
Vitamins & Sex Hormones
1
21.
National programmes including
2
Management of AIDS
Total Hours
100
DETAILED SYLLABUS OF PHARMACOLOGY
1) General Pharmacology
2) Autonomic Nervous System
- Sources of drugs
- Introduction to Automic Nervous System
- Routes of drug administration
- Adrenergic transmission
- Drug absorption
- Adrenergic drugs
- Drug distribution
- Adrenergic blocking agents
- Drug Bio transformation
- Cholinergic transmission
- Drug excretion
- Cholinergic drugs
- Methods of prolonging drug action
- Cholinergic blocking agents
- Mechanisms of drug action
- Anticholinesterases
- Factors modifying drug action
- Treatment of parkinsonism
- Bio-availability, Biological half-life,
- Treatment of Organophosphorous
Bioequivalence
poisoning.
- Adverse drug reactions
- Drug dependence
- Drug Interactions
- Structural activity relationship
- Clinical evaluation of a New drug
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3) Central Nervous System
4) Cardio vascular system
- Introduction of historical aspects,
- Cardiac glycosides
alcohols
- Anti arrhthmic agents
- General Anaesthetics, basal
- Anti hypertensives
anaesthesia of Premedication
- Anti anginal drugs
- Depressants - Barbiturates,
- Pharmacology of shock, Vasodilators and
Opioids, Benzodiazepines,
management of myocardial infarction,
Antipyretics and analgesics, (NSAIDS)
cardiogenic shock, left ventricular failure.
- Stimulants ? Central nervous system
- Plasma lipid lowering agents
stimulants and spinal stimulants
- Diuretics
Epilepsy and anticonvulsants
- Drug addiction
- Skeletal Muscle relaxants
- Local Anaesthetics
- Phychopharmacology
5) Autocoids
6) Miscellaneous topics
- Histamine, Antihistamines
- Heavy metal Poisoning
- Serotonin & its antagonists
- Environmental Poisoning
- Prostaglandins, Brady Kinins
- Hazards of smoking
- Polypeptidues, Rennin-Angiotensin
- Drugs of addiction
mechanism
- Geriatric Pharmacology
- Paediatric pharmacology
7) Chemotherapy
- Dermatological pharmacology
- Introduction and principles of
- General Principles of management of
Antinicrobial Therapy
Poisoning
- Sulfonamides, Cotrimoxazole and
- Drugs during pregnancy, Lactation
Fluroquinolones
- Drugs and preventive measures for AIDS, and
- Penicil ins and Newer Penicil ins
National World Health Organisation
- Cephalosporins
programmes.
- Macrolides and other Antibiotics
- Aminoglycosides Antibiotics
9) Blood
- Broad spectrum antibiotics
- Megaloblastic anaemias
- Chemotherapy of UTI
- Microcytic (Iron deficiency) Anaemias
- Antituberculosis drugs
- Anti coagulants
- Anti leprotic drugs
- Fibrinolytic agents & Anti platelet agents
- Anti fungal drugs
- Anti viral drugs & Chemotherapy of
10) Drugs acting on uterus
AIDS
- Uterine stimulants
- Anti Malarials
- Uterine relaxants
- Antiamoebic drugs
11) Respiratory system
- Chemotherapy of other Anti protozoal
- Cough suporessants & Mucolytic agents
infections
-Treatment of Bronchial Asthma
- Anthelminthics
- Antiseptics, Disinfectants and
ectoparasites
- Chemotherapy of neoplastic diseases.
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8) Drugs acting on Uterus, Respiratory 12) Hormones (Endocrinology)
System and G.I.T. & Blood
- Posterior pituitary hormones & related factors,
- Appetite stimulants & suppressants
ADH.
- Emetics & Anti emetics (Prokinetic
- Anterior pituitary growth hormones
agents)
- Thyroid hormone & Antithyroid drugs
- Anti diarrahoeal agents Treatment of
- Diabetes mellitus ? Insulin, oral Antidiabetic
diarrhoea
drugs and newer antidiabetic drugs
- Treatment of peptic ulcer
- Adrenal cortical Steriods ? Miners corticoids
- Purgatives
and synthetic steroids
- Parathyroid ? Parathormone ? Calcitonin ?
Calcium metabolism
- Sex hormones ? Estrogens, Progestins and
anti estrogens, antiprogestins
- Androgens ? Antiandrogens
Division of Pharmacology syllabus paper wise:
PAPER I : General Pharmacology, ANS, CNS, CVS AND drugs actings on renal systems.
PAPER II : Chemotherapy, hormones, GIT, Blood, Drugs acting on uterus, Heavy metal poisons,
Drugs for Resp. diseases.
ii PRACTICAL SYLLABUS (Pharmacology)
60 hours
This includes preparation of different dosage forms, formulations, prescription writing,
clinical Pharmacy exercises, problem bases clinical study of cases, drug interactions,
adverse drug reactions, demonstrations of the museum specimens attached to the
department, visit to a pharmaceutical company, bedside teaching.
EXPERIMENTAL PHARMACOLOGY DEMONSTRATION 60 hours
-
Effects of Cholinergic, adrenergic, histaminergic drugs and their antagonists on dogs.
-
Skeletal muscle relaxant effect in rabbits.
-
Opioid analgesic effect, straub's test in mice
-
Convulsant and anticonvulsant effects of certain drugs in rats and mice by different
methods.
-
General anaesthetic effect of ether of certain drugs in rats and mice by different methods
-
Analgesic and anti inflammatory effects of certain drugs in rats and mice by different
methods.
-
Prothromben time estimation
-
Respiratory function tests and the effect of drugs in their alteration ? Beta Blockers ?
Selective and non-selective.
-
General principles of spectroscopy, Colorimetry, Fluorimetry HPLC etc., with live
demonstration if possible
-
Clinical Pharmaco Kinetics:
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Study of half life of a drug, bio-availability etc., wherever facilities are available in the
college or local y at any other institute.
i i) CLINICAL ORIENTED PROBLEMS:
60 hours
-
Problem based learning (PBL)
-
Continuing Medical Education (CME)
-
Integrated teaching (ITC) classes
-
Seminars
-
Visit to Pharmaceutical firms
iv) Tutorials:
20 hours
The tutorial hours can be enhanced by reducing the same from either i), i ) or ii )
SUGGESTED STANDARD TEXT BOOKS
1. Pharmacology & Pharmacotherapeutics by Dr. Satoskar
2. Essentials of Medical Pharmacology by Dr. Tripathi.
REFERENCE BOOKS:
1. Applied & clinical Pharmacology by Rang Dale & Katzung.
2. Pharmacological basis of Therapeutics by Goodman & Gil man.
3. Clinical Pharmacology by Laurance.
4. Illustrated book in Pharmacology by Lippincott.
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This post was last modified on 28 June 2021