Download VNSGU (Veer Narmad South Gujarat University or South Gujarat University) MBBS ?(Bachelor of Medicine, Bachelor of Surgery) 2nd Year 2021 February Pharmacology Paper I Previous Question Paper
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IInd M.B.B.S. Examination
February - 2021
Pharmacology: Paper - 1 Set-I
Pharmacology IInd MBBS
Time: 2 Hours ]
[ Total Marks: 40
k|Q"p : / Instructions
(1)
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Seat No.:
Fill up strictly the details of signs on your answer book
Name of the Examination:
IInd M.B.B.S.
Name of the Subject :
Pharmacology: Paper - 1 Set-I Pharmacology IInd MBBS
Subject Code No.: 2006000102030001
Student's Signature
Section I
Q-1.
Answer the following.
[1*10=10]
a. Define `Pharmacovigilance' and mention one reason why it should be must.
b. Why is ipratropium bromide preferred over atropine for COPD
(chronic obstructive pulmonary disease)?
c. Name two conditions in which combination of neostigmine and atropine
is given?
d. Why nedocromil sodium should not be used for treatment of acute attack
of asthma?
e. Why frequency of administration of antacid administration is more in
comparison for required effect?
f. Write the drug of choice, its route and time of administration in motion
sickness in long journey.
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g. Explain why propranolol should be avoided in Prinzmetal angina?
h. Give rationale for starting heparin and warfarin together in acute
thromboembolic state.
i. Justify rationale of using Fixed Dose Combination (FDC)
Hydrochlorothiazide with spironolactone.
j. What is the mechanism of action of clonidine in Hypertension?
Q-2.
Answer any four of the following.
[2*4=8]
a. What is the effect of changing urinary pH on drug excretion?
Give one example for each for increase and decrease in pH.
b. Enumerate prostaglandin analogues and their therapeutic uses.
c. Mention various routes of administration of adrenaline with its
therapeutic indication.
d. Enumerate inotropic drugs. Explain the mechanism of action of Digoxin
and mention its side effects.
e. Describe role of inhalational corticosteroids in bronchial asthma and
explain why in status asthmaticus bronchodilator is more effective by
I/V route rather than inhalational route?
Section II
Q-3.
Answer any four of the following.
[3*4=12]
a. What is loading dose and maintenance dose? Explain with appropriate
drug example.
b. Enumerate alfa blockers. Mention uses and adverse effects of
Phentolamine.
c. Explain the concept of bioavailability. Describe various factors affecting
bioavailability.
d. Explain the role of ACE inhibitors in pharmacotherapy of congestive
heart failure. What is the status of digitalis in CHF?
e. Describe in detail different stages of dehydration due to diarrhea.
Describe treatment of moderate and severe dehydration.
Q-4.
Answer any two of the following.
[5*2=10]
a. Enumerate various iron preparations. Describe important features of
handling of iron by body after ingestion. Highlight the importance of
these features in relation to therapy of iron deficiency anemia.
b. Classify cholinomimetic agents. Write in detail about their therapeutic
uses giving pharmacological basis of each use and their adverse effects.
c. Enumerate various drugs from different categories for angina Describe
the mechanism of action, limitations, and adverse effects of nitrates for
classical angina
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This post was last modified on 28 December 2021