Download B.Pharm 3rd Year 2014 August 564264 Pharmacology I Question Paper

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(LF 4264) AUGUST 2014 Sub. Code: 4264
THIRD YEAR B.PHARM. EXAM
PAPER IV - PHARMACOLOGY -1
O.P. Code: 564264
Time: Three hours Maximum: 100 marks

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I. Essay: (2X20=40)
1. a) Define Bioassay. Mention the indications of bioassay and explain
about the types of bioassay.
b) Explain in detail about the bioassay of insulin and digitalis.
2. a) Define hypertension and give the types.

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b) Define and classify antihypertensive drugs with examples.
c) Explain in detail about Potassium channel activators and ACE inhibitors.

II. Short notes: (8X5=40)
1. Explain about Phase-I and II metabolic reactions.
2. Write in brief about the physiological factors which affect the drug

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absorption.
3. Centrally acting skeletal muscle relaxants.
4. Drugs indicated in Alzheimer’s disease.
5. Define Atherosclerosis and mention the drugs used in its treatment.
6. Principles of treatment of digitalis poisoning.

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7. Selective COX-2 inhibitors.
8. Drugs used in the treatment of Grand mal epilepsy.

III. Short Answers: (10X2=20)
1. Name two calcium channel blockers.
2. Name two ganglion blockers with their therapeutic uses.

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3. What is physiological antagonism? Give example.
4. Advantages of procainamide over procaine as an antiarrhythmic agent.
5. State therapeutic uses of Chlorpromazine.
6. What are the side effects of thiazides?
7. Advantages of using spironolactone.

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8. What are the contraindications to the use of Propranolol?
9. Name the neurotransmitters of the CNS.
10. Name two drugs used in the prophylaxis of asthma.

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