THIRD YEAR B.PHARM. EXAM
PAPER IV - PHARMACOLOGY -1
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Q.P. Code: 564264
Time: Three Hours Maximum: 100 marks
I. Elaborate on: (2X20=40)
- a) Classify the various routes of drug administration and explain in detail about the various injections.
b) Write a note on new drug delivery system - a) Define Parasympatholytics and classify it with examples for each group.
b) Describe the pharmacological actions, adverse effects and therapeutic uses of Atropine
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II. Write notes on: (8X5=40)
- Bioassay of oxytocin.
- Write in brief about acute and chronic alcoholism and give its mode of treatment
- Define Parkinsonism and classify the drugs used for it. Comment a note on Levodopa and Carbidopa combination.
- Write a note on drug addiction and drug habituation with examples.
- Explain about the nitrites and nitrates used as an antianginal drug.
- Explain about the sodium channel blockers used as an anti arrhythmic drug.
- Effect of enzyme induction and inhibition in drug metabolism.
- Write in brief about spiranolactone as a diuretic.
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III. Short Answers on: (10X2=20)
- Pharmacoepidemiology.
- Advantages of sublingual route.
- Give four examples of drugs with low therapeutic index and high rate of adverse drug reactions.
- Receptor down regulation.
- Mechanism of action of succinylcholine.
- Four therapeutic uses of Analeptics.
- Name four hallucinogens.
- Mention four drugs known to cause bronchospasm.
- Name four common causes of inadequate response to antihypertensive treatment.
- Hypovolemic or Oligemic shock.
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