Download B.Pharm 3rd Year 2014 February 564266 Pharmaceutical Biotechnology Question Paper

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THIRD YEAR B.PHARM. EXAM

(Common to Regulations 2004 — IV year candidates)

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PHARMACEUTICAL BIOTECHNOLOGY

Q.P. Code: 564266

Time: Three Hours Maximum: 100 marks

1. I. Elaborate on: (2X20=40)

   1. Define disinfection. Classify them with examples and write their mechanism of action.

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   2. Differentiate dry heat and filtration sterilization
2. 1. Production of penicillin by fermentation.
   2. Poliomyelitis vaccine.

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3. II. Write notes on: (8X5=40)

   1. Explain about the structures external to the cell wall.
   2. Types of biotransformation reactions.
   3. Auto immune disorders
   4. Small pox vaccine preparation and evaluation.

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   5. Cloning strategies.
   6. Quantitative estimation of antigen and antibody.
   7. Techniques in immobilization of enzyme.
   8. Screening method in fermentation process.

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4. III. Short Answers on: (10X2=20)

   1. Classification of micro-organism based on temperature.
   2. List some sterile pharmaceutical products.
   3. Chick-Martin test.
   4. Insertion sequences

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   5. Application of Biotransformation.
   6. Haptens
   7. Triple Vaccines
   8. Northen blot
   9. Official Parameters in fermentation process

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   10. Component of Biosensor

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