B.PHARM. DEGREE EXAMINATION
THIRD YEAR
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PAPER IV - PHARMACOLOGY - I
Q.P. Code: 564264
Time : Three Hours Maximum : 100 marks
Answer All Questions
- Essay: (2x20=40)
- Classify Diuretics. Write the pharmacological actions, therapeutic uses and adverse effect of chlorthiazides. Add a note on hypertension therapy.
- Define biotransformation. Explain in detail different phases of biotransformation reactions.
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- Short notes : (8 x5=40)
- Write the pharmacological actions of atropine in eye and smooth muscles.
- Write the pharmacological action of alpha and beta adrenergic blockers on heart and blood pressure.
- Write briefly on chlorpromazine.
- Discuss the mechanism of action and therapeutic uses of lignocaine.
- Briefly discuss the pharmacological action of chlorpromazine in CNS.
- Give the therapeutic uses of narcotic analgesics.
- Classify sedatives with example. State the mechanism of action of diazepam.
- Give one example and one therapeutic use for the following group of drugs.
- Cardioselective ß blocker
- SSRI
- Potassium channel blocker
- COX 2 inhibitor
- Aldosterone antagonist.
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- Short answers: (10x 2=20)
- Give two therapeutic uses of adrenaline.
- Give two examples of drugs used in the treatment of arrhythmias.
- Explain the mechanism of action of atorvastatin.
- Name two inhalational general anaesthetics.
- Give one example each for antipyretics and non narcotic analgesic.
- Give the side effects of haloperidol.
- What is amitriptyline?
- Define bioassay.
- Write the mechanism of actions of carbamazepine.
- What is Pal IrarT GEUIIIDL. OTVG \/Aallll.\/?
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