[LH 4269] AUGUST 2015 Sub. Code: 4269
B.PHARM. DEGREE EXAMINATION
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FOURTH YEARPAPER III ? PHARMACOLOGY - II
Q.P. Code: 564269
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Time : Three Hours
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Maximum : 100 marks
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Answer ALL questionsI. Essay:
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(2 x 20 = 40)1. a) Classify Anti-Emetics.
b) Discuss the mechanism of action, side effects and uses of each class of anti emetics.
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2. a) Classify Anti-malarial.
b) Describe the mechanism of action, therapeutic uses and adverse effects of
chloroquine.
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c) Write a note on drugs used in prophylaxis of malaria.
II. Short notes :
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(8 x 5 = 40)
1. Describe the steps involved synthesis and metabolism of bradykinin.
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2. Describe the Mechanism of action, therapeutic uses and adverse effect of cyclosporine.3. Describe the Mechanism of action therapeutic uses and adverse effect of Gentamycin.
4. Write a note on Metformin.
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5. Explain the general methods for treatment of poisoning.
6. Write briefly on oral contraceptives.
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7. What are fibrinolytics? Classify them and give their therapeutic application.8. Write a note on drugs used in the treatment of AIDS.
III. Short answers:
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(10 x 2 = 20)1. Name two macrolides, antibiotics.
2. What is pentagastrin?
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3. What are the drugs used in the treatment of glaucoma?
4. Define sub acute toxicity.
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5. Side effects of chloramphenicol.6. Name two appetite stimulants
7. Name two Prokinetic agents.
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8. Define the term mutagenicity.
9. Name two bulk purgatives.
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10. Name two topical sulphonamides.*******