Download B.Pharm 4th Year 2015 August 564270 Modern Methods of Pharmaceutical Analysis Question Paper

[LH 4270] AUGUST 2015 Sub. Code: 4270

B.PHARM. DEGREE EXAMINATION

--- Content provided by FirstRanker.com ---

FOURTH YEAR

PAPER IV ? MODERN METHODS OF PHARMACEUTICAL ANALYSIS

Q.P. Code: 564270

--- Content provided by FirstRanker.com ---

Time : Three Hours

--- Content provided by FirstRanker.com ---

--- Content provided by FirstRanker.com ---

Maximum : 100 marks

--- Content provided by FirstRanker.com ---

Answer ALL questions

I. Essay:

--- Content provided by FirstRanker.com ---

--- Content provided by FirstRanker.com ---

--- Content provided by FirstRanker.com ---

--- Content provided by FirstRanker.com ---

(2 x 20 = 40)

1. a) Write the theory and instrumentation of Polarography.

b) Write the deviations from Beer's law.

--- Content provided by FirstRanker.com ---

c) Write the sampling techniques used in IR spectrophotometry.

2. a) Explain the detectors used in Gas Chromatography.

--- Content provided by FirstRanker.com ---

b) Explain in detail about chemical shift and spin-spin coupling.

II. Short notes :

--- Content provided by FirstRanker.com ---

--- Content provided by FirstRanker.com ---

--- Content provided by FirstRanker.com ---

--- Content provided by FirstRanker.com ---

(8 x 5 = 40)

1. Write a note on Radio immuno Assay.

2. What are the methods used to find the distance between the crystal plane by X ?ray

--- Content provided by FirstRanker.com ---

diffraction analysis? Explain the working of Bragg's spectromete

3. Write a note on electron impact ionization.

--- Content provided by FirstRanker.com ---

4. How will you measure conductance? Explain with neat diagram.

5. Write the different types of electrodes used in electrochemical methods of analysis.
Explain the construction and working of Saturated Calomel Electrode.

--- Content provided by FirstRanker.com ---

6. Write a note on moving boundary electrophoresis.

7. Explain the factors affecting the intensity of fluorescence.

8. How will you calculate max by Woodward ? Fischer rule?

--- Content provided by FirstRanker.com ---

III. Short answers:

--- Content provided by FirstRanker.com ---

--- Content provided by FirstRanker.com ---

--- Content provided by FirstRanker.com ---

(10 x 2 = 20)

1. Define Equivalent conductance

--- Content provided by FirstRanker.com ---

2. What is Reverse Phase Chromatography?

3. Define Resolution

--- Content provided by FirstRanker.com ---

4. List any two stationary phase used in TLC.

5. Define RF value and Rx value

6. Mention the light source and detectors used in AAS.

--- Content provided by FirstRanker.com ---

7. List any four detectors used in IR spectroscopy.

8. Define Quenching.

--- Content provided by FirstRanker.com ---

9. Define Bathochromic shift and Hypsochromic shift.

10. Define Electrode potential. Mention example for indicator electrode.

*******

--- Content provided by FirstRanker.com ---