Download B.Pharm 4th Year 2016 August 564267 Formulative Pharmacy And Biopharmaceutics Question Paper

Download B.Pharmacy (Bachelor of Pharmacy) 4th Year (Final Year) 2016 August 564267 Formulative Pharmacy And Biopharmaceutics Previous Question Paper

(LJ 4267)





AUGUST 2016 Sub. Code: 4267



FOURTH YEAR B.PHARM. EXAMINATION

PAPER I ? FORMULATIVE PHARMACY AND BIOPHARMACEUTICS



Q.P. Code: 564267

Time: Three hours







Maximum: 100 Marks

I. Essay: (2 x 20 = 40)


1. Give an account of stability testing protocol for various pharmaceutical products.

How drug products can be stabilized from the influence of oxidation?


2. Explain about Bio-availability testing.


II. Short notes:

(8 x 5 = 40)



1. Study of particle size and density of drugs in preformulation studies.
2. Soft gelatin capsule shell and content.
3. Coacervation phase separation.
4. Tablet excipients.
5. Formulation of film coating solutions.
6. Benefits and limitations of prolonged action Pharmaceuticals.
7. Osmotic drug delivery systems.
8. Biological factors influencing gastrointestinal absorption of drugs.



III. Short answers:











(10 x 2 = 20)



1. Significance of drug solubility.
2. Quality control tests on capsules.
3. Methods of microencapsulate liquids.
4. Sticking and picking in film coated tablets.
5. Difference between prolonged (sustained) release and controlled

release drug delivery systems.

6. Properties of drugs suitable for transdermal drug delivery systems.
7. Raw materials required for liposomes.
8. Apparent volume of distribution.
9. Parameters affecting drug dissolution.
10. Dissolution testing apparatuses.




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