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B.PHARM. DEGREE EXAMINATION
FOURTH YEAR
PAPER IV ? MODERN METHODS OF PHARMACEUTICAL
Q.P. Code: 564270
Time: Three hours
Maximum: 100 Marks
I. Elaborate on:
1. a) Explain the principle of NM What ar e the conditions for nuclei to exhibit
nuclear magnetic resonance?
b) Explain the terms chemically equivalent protons, shielding and deshielding,
splitting of signals.
2. a) Explain the components of a Gas-Liquid Chromatography assembly and
explain its working.
b) What are the different types of columns used in GLC? Explain.
II. Write notes on:
(8 x 5 = 40)
1. Describe the components of a Nephelomete
2. What are the factors that affect fluorescence?
4. Explain the construction and working of the standard calomel electrode.
5. Explain the principle of counter current extraction.
6. Explain `Dead Stop End Point Titrations'.
7. Outline the basic concept of Total Quality Management.
degrees of freedom for a linear molecule and a non linear molecule.
(10 x 2 = 20)
1. Name two solvents frequently used in Reverse phase HPLC.
2. Differentiate between Isocratic system and gradient elution system.
3. What are the conditions for the absorption of Infra-Red radiation?
4. What is molecular ion peak?
6. What is Gel filtration?
7. What is equivalent conductance?
8. What is half wave potential on a polarogram?
9. Give two applications of Turbidometric assays.
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B.PHARM. DEGREE EXAMINATION
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FOURTH YEAR
PAPER IV ? MODERN METHODS OF PHARMACEUTICAL
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ANALYSISQ.P. Code: 564270
Time: Three hours
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--- Content provided by FirstRanker.com ---
Maximum: 100 Marks
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I. Elaborate on:
--- Content provided by FirstRanker.com ---
(2 x 20 = 40)1. a) Explain the principle of NM What ar e the conditions for nuclei to exhibit
--- Content provided by FirstRanker.com ---
nuclear magnetic resonance?
b) Explain the terms chemically equivalent protons, shielding and deshielding,
splitting of signals.
--- Content provided by FirstRanker.com ---
2. a) Explain the components of a Gas-Liquid Chromatography assembly and
explain its working.
b) What are the different types of columns used in GLC? Explain.
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II. Write notes on:
(8 x 5 = 40)
--- Content provided by FirstRanker.com ---
1. Describe the components of a Nephelomete
2. What are the factors that affect fluorescence?
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3. Describe the construction and working of a hollow cathode lamp.4. Explain the construction and working of the standard calomel electrode.
5. Explain the principle of counter current extraction.
6. Explain `Dead Stop End Point Titrations'.
7. Outline the basic concept of Total Quality Management.
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8. Discuss how we may arrive at a formula to determine the number of vibrationaldegrees of freedom for a linear molecule and a non linear molecule.
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III. Short answers on:(10 x 2 = 20)
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1. Name two solvents frequently used in Reverse phase HPLC.
2. Differentiate between Isocratic system and gradient elution system.
3. What are the conditions for the absorption of Infra-Red radiation?
4. What is molecular ion peak?
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5. What is a Guard Column used in HPLC?6. What is Gel filtration?
7. What is equivalent conductance?
8. What is half wave potential on a polarogram?
9. Give two applications of Turbidometric assays.
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10. What is X-ray diffraction?********
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