Preli
First Year MBBS Examination
I MBBS Biochemistry Paper 1
Time: 3 hours
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Max Marks: 50Instructions: 1. Answer to the points. 2. Figure
to the right indicates marks. 3. Use separate
answer books for each section. 4. Draw
diagrams wherever necessary. 5. Write legibly.
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Section 11. Write short notes on: (any two) (10)
a) Mention various types of abnormal
Hemoglobin. Discuss sickle cell anemia
b) Discuss enzyme Inhibition with suitable
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examplesc) Describe the principle types & applications of
Electrophoresis
2. Write Short notes on (any three) (9)
a) Active transport
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b) Eicosanoidsc) Metabolic Acidosis
d) Lipoproteins
e) Fluid mosaic model
3. Write Short notes on (any two) (6)
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a) Renal mechanism in maintenance of normalacid base balance
b) Renal function test
c) Applications of enzymes
Section 2
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4. Write Short notes on (any two) (10)a) Electron transport chain & its inhibitors
b) Describe Diabetes Mellitus & its
complications
c) p Oxidation of Palmitic acid
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5. Write Short notes on (any three) out of five)(9)
a) Tumor markers
b) Health hazards of water pollution
c) Glycogen storage disease
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d) Uncouplerse) Mucopolysaccharides and its disorders (A.
98) (C.22)
6. Read the case report and answer the
following questions (any six): A 37 year old
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male was admitted in a hospital in Patan withcomplaints of pain in abdomen, (6)
anorexia, vomiting and passing yellow colored
urine since 10 days. On examination liver was
tender and palpable icterus was seen his LFT
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reports were. Serum Alaninetransaminase (ALT):3971 IU/L (Normal 0-40
IU/L) Scrum Aspartate transaminase
(AST):3148 IU/L (normal: 3-13 kA units) Scrum
Alkaline phosphate (ALP):27 kA units
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(Normal 3-3 mg/dl) Scrum Bilirubin Total:22mg/dl (Normal 0.3-3 mg/dl) Scrum Bilirubin
Direct;12 mg/dl (Normal 0-2-0-8 mg/dl)
a) Which are the different types of jaundices?
b) Write clinical significance of serum bilirubin.
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c) Write the causes of jaundicesd) Name the bile salts and bile pigments
e) Enlist the other LFTs apart from mention
above
f) What is van den Bergh reaction and what is
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its significance in differential diagnosis ofjaundice?
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