Preli
First Year MBBS Examination
I MBBS Biochemistry Paper 1
Time: 3 hours
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MaxMarks: 50
Instructions: 1. Answer to the points. 2. Figure to the right
indicates marks. 3. Use separate answer books for each
section. 4. Draw diagrams wherever necessary. 5. Write
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legibly.Section 1
1. Write short notes on: (any two) (10)
a. Discuss Oxidative Phosphorylation and mention
Uncouples
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b. What are enzymes? Discuss the factors affectingenzyme action
c. Mention the various types of abnormal hemoglobin and
discuss sickle cell disease
2. Write Short notes on (any three) (9)
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a. Diagnostic Importance of Enzymeb. Prostaglandins
c. Glycoproteins
d. Phospholipids
e. 2,3 BPG and its clinical significance
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3. Write Short notes on (any two) (6)a. Liver function test
b. Role of kidney in acid base balance
c. Electrophoresis
Section 2
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4. Write Short notes on (any two) (10)a. Beta oxidation of fatty acids
b. Glycolysis and its regulation with energetic
c. Metabolic fate of Acetyl CoA
5. Write Short notes on (any three) out of five) (9)
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a. Give causes, sources and health hazards of airpollution
b. Immunoglobulin
c. Proto-oncogenes and Oncogenes
d. Free radicals and importance of antioxidants
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e. ATP6. Write Justification of following statements: (any six) (6)
a. Cellulose cannot be digested and absorbed by human
b. LDH is not the preferable test in myocardial infarction
(MI)
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c. Fluoride is used as an anticoagulant for blood sugarestimation
d. Role of Pravastatin in cholesterol synthesis
e. HDL is a good Cholesterol and LDL is known as a bad
cholesterol
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f. Personal with sickle cell trait are resistant to malariacaused by plasmodium falciparum.
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