Date: 11-12-2016
Preli
First Year MBBS Examination
I MBBS Biochemistry Paper 2
Time: 3 hours
Instructions: 1. Answer to the points. 2. Figure
to the right indicates marks. 3. Use separate
answer books for each section. 4. Draw
diagrams wherever necessary. 5. Write legibly.
1. Give an account of any two (10)
a. Detoxification of ammonia and disorders of
urea cycle
b. PCR technique & its medical applications
levels and deficiency manifestations of
vitamin
2. Write Short notes on (any three) (9)
a. Post translations modifications
b. Genetic Code
c. Structure & functions of t-RNA
d. Gene expression & explain Lac Operon
e. Southern blot technique
3. Explain any two (6)
b. Importance of dietary fibers
c. Protein energy malnutrition
Section 2
4. Write briefly on (any two) (10)
b. Fate and functions of Methionine and
cysteine amino acids
c. Inborn errors of Phenylalanine and tyrosine
amino acid metabolism
five) (9)
a. Biochemical functions of vitamin C
b. Biologically active nucleotides
c. Wald's visual cycle
e. Antioxidant vitamins
6. Read the case report and answer the
following questions (6)
A 37 year old male was admitted in a hospital in
Anorexia vomiting and passing yellow colored
urine since 10 days. On examination liver was
tender and palpable. Icterus was seen his LFT
reports were. Scrum Alnine transaminase (ALT)
transminased (AST) 3148 IU/L (Normal Q-4Q
IU/L) Scrum Alkaline phosphate (ALP)27 kA
units (Normal 3-13 kA units) Scrum Bilirubin
Total 22 mg/dl (Normal: 0.3-3 mg/dl) Scrum
a. Which are the different types of Jaundices?
b. Write clinical significance of serum bilirubin.
c. Write the causes of jaundices
d. Name the bile salts and bile pigments
above
f. What is van den Bergh reaction and write
what is its significance in differential
diagnosis of jaundice?
Preli
First Year MBBS Examination
I MBBS Biochemistry Paper 2
Time: 3 hours
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Max Marks: 50Instructions: 1. Answer to the points. 2. Figure
to the right indicates marks. 3. Use separate
answer books for each section. 4. Draw
diagrams wherever necessary. 5. Write legibly.
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Section 11. Give an account of any two (10)
a. Detoxification of ammonia and disorders of
urea cycle
b. PCR technique & its medical applications
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c. Role of Vitamin D in regulation blood calciumlevels and deficiency manifestations of
vitamin
2. Write Short notes on (any three) (9)
a. Post translations modifications
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b. Genetic Code
c. Structure & functions of t-RNA
d. Gene expression & explain Lac Operon
e. Southern blot technique
3. Explain any two (6)
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a. Metabolic adaptation during starvationb. Importance of dietary fibers
c. Protein energy malnutrition
Section 2
4. Write briefly on (any two) (10)
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a. Hyperuricemia and Goutb. Fate and functions of Methionine and
cysteine amino acids
c. Inborn errors of Phenylalanine and tyrosine
amino acid metabolism
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5. Write Short notes on (any three) out offive) (9)
a. Biochemical functions of vitamin C
b. Biologically active nucleotides
c. Wald's visual cycle
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d. One carbon metabolisme. Antioxidant vitamins
6. Read the case report and answer the
following questions (6)
A 37 year old male was admitted in a hospital in
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Patan with complaints of Pain in abdomen.Anorexia vomiting and passing yellow colored
urine since 10 days. On examination liver was
tender and palpable. Icterus was seen his LFT
reports were. Scrum Alnine transaminase (ALT)
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2971 JU/L (Normal: Q-40 ig/L) Scrum Aspartatetransminased (AST) 3148 IU/L (Normal Q-4Q
IU/L) Scrum Alkaline phosphate (ALP)27 kA
units (Normal 3-13 kA units) Scrum Bilirubin
Total 22 mg/dl (Normal: 0.3-3 mg/dl) Scrum
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Bilirubin Direct:12 mg/dl (Normal 0.2-0.8 mg/dl)a. Which are the different types of Jaundices?
b. Write clinical significance of serum bilirubin.
c. Write the causes of jaundices
d. Name the bile salts and bile pigments
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e. Enlist the other LFT's apart from mentionabove
f. What is van den Bergh reaction and write
what is its significance in differential
diagnosis of jaundice?
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***Document Outline
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