Instructions:
1. Answer to the points.
2. Figure to the right indicates marks.
3. Use separate answer books for each section.
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4. Draw diagrams wherever necessary.5. Write legibly.
First Year MBBS Examination
I MBBS Biochemistry Paper 1
Time: 3 hours
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Max Marks:50
Section 1
1. Write short notes on: (any two) (10)
a) Diagnostic biomarkers in acute myocardial
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infarctionb) Jaundice
c) Role of hormones in regulation of blood
glucose
2. Write Short notes on (any three) (9)
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a) Metabolic acidosisb) Importance of HMP shunt
c) Sickle cell anemia
d) Pyruvate dehydrogenase complex
3. Write Short notes on (any two) (6)
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a) Renal function testb) Structure and function of Immunoglobulin
c) Fatty liver
Section 2
4. Write Short notes on (any two) (10)
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a) Describe reactions energetic importance ®ulation of Citric acid cycle.
b) What are Lipoproteins? Explain the role of
HDL in lipoprotein metabolism
c) Explain electron transport chain & its
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inhibitors5. Write Short notes on (any three) out of five)
(9)
a) -Oxidation of Palmitic acid
b) Glycogen storage disease
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c) Air pollution and their adverse effectsd) Oncogenic viruses
e) Ketone bodies
6. Case Give answers of any six:A 45 years old
obese business man with compliment of
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excessive hunger, thirst, urination and non-healing injury of lower leg was consulted by
physician. Before starting treatment suggest.
(6)
a) What is the probable diagnosis, justify
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b) What investigation to be done in blood forconfirmation of diagnosis
c) What investigation to be done in urine
sample
d) Suggest special investigation for monitoring
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during treatmente) What is the reason for excessive hunger,
thirst & urination?
f) What is the reason for non-healing injury?
g) Indicate other abnormalities likely to be
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developed if disease is not properly managed.h) What advice regarding diet to be given
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