First Year MBBS Examination
I MBBS Biochemistry Paper 2
Date: 07-12-2018
Time:
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3 hoursMax Marks: 50
Instructions: 1. Answer to the points. 2. Figure to the
right indicates marks. 3. Use separate answer books
for each section. 4. Draw diagrams wherever
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necessary. 5. Write legibly.Section 1
1.Give an account of: (any two) (10)
a. Biochemical functions and deficiency
manifestations of thiamin (A. 471) (C. 135)
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b. Structural features of DNAc. Protein malnutrition disorders (A. 516) (C.516)
2.Write Short notes on (any three) (9)
a. Post transitional modifications (A. 572) (C. 547)
b. Genetic code (A. 580) (C.551)
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c. Principle and applications of PCR (A. 612)(C.594)
d. Mutations (A. 591) (C.535)
e. Gene therapy (A. 604) (C.625)
3.Write Short notes on (any two) (6)
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a. Metabolism in starvation (A. 122) (C. 383)b. Importance of carbohydrates in diet (A. 513)
(C.506)
c. BMR (A. 512) (C.504)
Section 2
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4.Give an account on (any two) (10)a. Detoxification of ammonia (A. 258) (C. 335)
b. Regulation of iron tumover and its disorders
c. Phenylketonuria
5.Write Short notes on (any three) (9)
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a. Pellagra (A. 470) (C.141)b. Allopurinol is used in treatment of hyperuricemia.
Why?
c. Scurvy (A. 482) (C.134)
d. Antioxidant vitamins (A. 429) (C. 659)
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e. Salvage pathway of purines (A. 546) (C. 391)6.Write Short notes of (any six) (6)
a. Glutamate is regarded as "collection centre" of
amino group
b. Dietary fiber should be consumed in diet
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c. t-RNA plays an important role in translation (A.578) (C. 81)
d. Raw eggs should not be consumed
e. For Parkinson disease DOPA is used not
dopamine as a line of treatment
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f. Albumin is used as an antidote for heavy metalpoisoning
g. Orotic aciduria is a disorder of pyrimidine
metabolism
h. Vitamin K helps in blood coagulation
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