Date: 12-10-2018
MGR 5505
First Year MBBS Examination
I MBBS Biochemistry Paper 1
Time: 3 hours Max Marks: 50
to the right indicates marks. 3. Use separate
answer books for each section. 4. Draw
diagrams wherever necessary. 5. Write legibly.
Section 1
a. Thalassemia (A. 347) (C. 206): Molecular
basis, Types and symptoms
b. Enzymes Inhibition (A. 63) (C.92):
Competitive, Noncompetitive
Compensatory Mechanism
2. Write Short notes on (any three) (9)
a. Significance of Conjugated and Unconjugated
Bilirubin
c. Isoenzymes (A. 79) (C.112)
d. Diagnostic and Therapeutic uses of
Polysaccharides
e. Substrate specificity of enzymes
a. Blood buffers and their role (A. 398) (C. 475)
b. Spectrophotometer and its significance
c. Role of Lysosomes (A. 12) (C.7) and
Peroxisomes
4. Write Short notes on (any two) (10)
a. HMP shunt and G6PD deficiency (A. 144) (C.
270)
b. Beta oxidation of fatty acids (C16) with its
c. Lipid profile and its significance
5. Write Short notes on (any three) out of five)
(9)
a. Oxidative phosphorylation (A. 318) (C.228)
c. Oncogenes (A. 664) (C.687)
d. Primary antibody-structure and functions
e. Carcino-emryonic antigen (CE (A. 667)
(C.691)
(any six) (6)
a. Being product of the same gene Apo B 48
and Apo B-100 are different in composition
and functions
c. CPK has only 3 isoforms
d. cAMP is called as second messenger
e. Glycosylated hemoglobin test has a
prognostic importance in diabetic patients
mechanism
g. Liver cannot use ketone bodies
***
MGR 5505
First Year MBBS Examination
I MBBS Biochemistry Paper 1
Time: 3 hours Max Marks: 50
--- Content provided by FirstRanker.com ---
Instructions: 1. Answer to the points. 2. Figureto the right indicates marks. 3. Use separate
answer books for each section. 4. Draw
diagrams wherever necessary. 5. Write legibly.
Section 1
--- Content provided by FirstRanker.com ---
1. Write short notes on: (any two) (10)a. Thalassemia (A. 347) (C. 206): Molecular
basis, Types and symptoms
b. Enzymes Inhibition (A. 63) (C.92):
Competitive, Noncompetitive
--- Content provided by FirstRanker.com ---
c. Acidosis and Alkalosis: Causative factors,Compensatory Mechanism
2. Write Short notes on (any three) (9)
a. Significance of Conjugated and Unconjugated
Bilirubin
--- Content provided by FirstRanker.com ---
b. Importance of Polyunsaturated Fatty acidsc. Isoenzymes (A. 79) (C.112)
d. Diagnostic and Therapeutic uses of
Polysaccharides
e. Substrate specificity of enzymes
--- Content provided by FirstRanker.com ---
3. Write Short notes on (any two) (6)a. Blood buffers and their role (A. 398) (C. 475)
b. Spectrophotometer and its significance
c. Role of Lysosomes (A. 12) (C.7) and
Peroxisomes
--- Content provided by FirstRanker.com ---
Section 24. Write Short notes on (any two) (10)
a. HMP shunt and G6PD deficiency (A. 144) (C.
270)
b. Beta oxidation of fatty acids (C16) with its
--- Content provided by FirstRanker.com ---
energetics (A. 194) (C.287)c. Lipid profile and its significance
5. Write Short notes on (any three) out of five)
(9)
a. Oxidative phosphorylation (A. 318) (C.228)
--- Content provided by FirstRanker.com ---
b. Air pollution and its effects (A. 534) (C.663)c. Oncogenes (A. 664) (C.687)
d. Primary antibody-structure and functions
e. Carcino-emryonic antigen (CE (A. 667)
(C.691)
--- Content provided by FirstRanker.com ---
6. Write Justification of following statements:(any six) (6)
a. Being product of the same gene Apo B 48
and Apo B-100 are different in composition
and functions
--- Content provided by FirstRanker.com ---
b. Insulin is anabolic hormonec. CPK has only 3 isoforms
d. cAMP is called as second messenger
e. Glycosylated hemoglobin test has a
prognostic importance in diabetic patients
--- Content provided by FirstRanker.com ---
f. Thermogenin produces heat-state itsmechanism
g. Liver cannot use ketone bodies
***