First Year MBBS Examination
I MBBS Biochemistry Paper 2
Time: 3 hours Date: 06-12-2016 Max Marks: 50
Instructions: 1. Answer to the points. 2. Figure to the
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right indicates marks. 3. Use separate answer booksfor each section. 4. Draw diagrams wherever
necessary. 5. Write legibly.
Section 1
1. Give an account of: (any two) (10)
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a. Gout and its treatment policies (A. 548) (C.394)
b. Detoxification of ammonia and disorders of
urea cycle (A. 258) (C. 335)
c. DNA repair mechanisms (A. 562) (C. 537)
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2. Write Short notes on (any three) (9)a. Structure and types of DNA
b. Post transnational modification (A. 572) (C.
547)
c. Polymerase chain reactions and its application
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d. Gene therapy (A. 604) (C.625)e. Conjugation reactions of detoxification (A.
525) (C. 640)
3. Write Short notes on (any two) (6)
a. Role of fibers in the diet (A. 514) (C. 508)
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b. Fate of acetyl CoAc. Protein energy malnutrition
Section 2
4. Give an account on (any two) (10)
a. Discuss Ascorbic acid with Dietary sources,
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biochemical functions and deficiency symptoms(A. 481) (C. 132)
b. Inborn errors of Phenylalanine and tyrosine
amino acid. (A. 292) (C. 351)
c. Describe copper metabolism in body-sources,
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biochemical functions and abnormalities5. Write Short notes on (any three) (9)
a. Pernicious Anemia in Vit B12 deficiency
b. Glycemic index
c. Biochemical role of Selenium
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d. Formation of Uric acid (A. 547) (C.392)e. Disorders of Pyrimidine metabolism
6. Answer in few lines: Any six (6)
a. Denatured proteins are biologically inactive.
b. Nitric acid is called as a double edged sword.
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c. Acetyl coenzymes A considered the molecule ofmetabolic integration
d. Incidence of pellagra is more common in
women
e. The requirement of iron in the diet is ten times
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the body's requirement.
f. Vitamin K cart be used as antidote to warfarin
poisoning
g. The action of enzyme telomerase is linked with
aging
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h. RNA synthesis is not as meticulouslymonitored as DNA synthesis
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