First Year MBBS Examination
I MBBS Biochemistry Paper 1
Time: 3 hours Date: 06-02-2015 Max Marks: 50
Instructions: 1. Answer to the points. 2. Figure
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to the right indicates marks. 3. Use separateanswer books for each section. 4. Draw
diagrams wherever necessary. 5. Write legibly.
Section 2
5.Write Short notes on (any three) (9)
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a. Biochemical functions of Pyridoxalphosphate
b. mUCOPOlysaccharides and related disorders
c. Biological role of proteins
d. Vitamin D3
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e. Acid base balance6.Write Short notes of (any six): A 60 year old
was admitted in hospital with complaints of
bleeding per rectum,abdominal pain, weakness
alteration in bowel habit. On (6) examination
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palpable lump on left lumbar region felt, bloodreports as follow Blood Hemoglobin 7.0. gm/dl
(14-16 gm/dl) Serum carcinoembryogenic
antigen level - 10 ug/l (Normal: 3-5 ug/l) By
other investigation patient was diagnosed for
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colon carcinoma.a. What is the importance of estimation of
Carcinoembryogenic antigen?
b. What are tumor markers? Give other two
examples (A. 666) (C.691)
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c. Define proto-oncogens and tumor suppressorgenes.
d. What is difference between oncogens and
oncogenes?
e. What is chemotherapy? Give any one
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example.f. Which are causative agents of cancer?
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