Second Year MBBS Examination
II MBBS Pathology Paper 1
Date: 07-06-2017 Time: 2 hours
Max
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Marks: 40Instructions:
1. Answer to the points.
2. Figure to the right indicates marks.
3. Use separate answer books for each section.
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4. Draw diagrams wherever necessary.5. Write legibly.
Section 1
1. MCQ (10)
a. Mutation affecting germ cells produce: (a) Cancers (B)Inherited diseases
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(c)Congenital Malformations (D)Aneuploidyb. Most common hereditary coagulation disorder is:(A)Hemophilia A
(B)Hemophilia B (C)von Willebrand disease (D)Protein C deficiency
c. Basophils are increased in: (A) Bronchial asthma (B)Chronic Myeloid
Leukemia (C)Pneumonia (D)Corticosteroid therapy
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d. (A)Edward Jenner (B) Hippocrates (C)Karl Landsteiner (D)Laennece. In cell cycle signal transduction system is activated by(a) G protein
receptors(b) Selectins(c) Cadherins(d) Integrins
f. In hereditary spherocytosis following membrane structure is deficient: (a)
Band 3 protein(B) Glycophorin(c) Spectrin(d) Glycolipid
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g. Which of the following gene is proapoptotoic? (a) p53 (b) Bel-2 (c) RB (d)Bax
h. In iron deficiency anemia TIBC is: (a) Low(b) High(c) Normal (d) Borderline
i. The most common form of amyloid in developing countries is:(a) Primary (b)
Secondary (c) Localised (d) Hereditary
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Section 22. Write short notes on: (two out of three) (10)
a. Describe intracellular accumulation. Write fatty change in detail.
b. Write about factors influencing tissue repair.
c. Disseminated intravascular coagulation.
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3. Write briefly on: (four out of five) (10)a. Laboratory diagnosis of Chronic Myeloid Leukemia.
b. Hemolytic anaemia due to intracellular etiology.
c. Fresh frozen plasma.
d. Rh blood group system.
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4. Write short notes on: (two out of three) (10)a. Paraneoplastic syndrome.
b. Granulomatous inflammation.
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