MCT 7014
Second Year MBBS Examination
II MBBS Pathology Paper 1 (New)
Time: 3 hours Max Marks: 100 Date: 06-01-2023
Instructions: 1. Answer to the points.
3. Use separate answer books for each section.
4. Draw diagrams wherever necessary.
5. Write legibly.
Section 1
two) (10)
a) Enumerate causes of cell injury. Describe
pathogenesis and morphology of cell injury.
b) Enlist the chemical mediators of acute
mediators of acute inflammation. Write different
between acute and chronic inflammation.
2A.Applied short notes: (two out of three) (12)
a) Describe pathogenesis, Enumerate route of
b) A 55 year old lady was brought to the emergency
room unconscious. Her blood pressure was very low,
pulse was weak and rapid. Her skin was warm and
flushed. Her blood culture revealed growth of Gram
(b) Describe the pathogenesis of thig condition. (c)
Describe the stages of this disorder.
c) Define Metastasis. Describe routes and
mechanism of metastasis.
a) Define Obesity. Describe etiopathogenesis and
metabolic effect of obesity.
b) Define Gangrene. Describe pathophysiology of
gangrene and difference between Wet and dry
d) Define and classify amyloidosis and describe
morphology of amyloid Spleen.
3.Answer in two to three sentences only: (five out
of Six) (10)
b) Define Autonomy.
c) Enlist the sPectrum of autoantibodies in SLE,
d) Define metaplasia and give two examples of it.
e) Give four ,-xamples hypertrophy.
Section 2
4. Structured long answer question:(one out of
two) (10)
a) Classify Anemia. Describe pathogenesis
Sickle cell anemia.
b) Define chronic myeloid leukemia. Describe
etiology, clinical features and laboratory findings of
CML.
a) 20 year female come to OPD with complain of
weakness, easy fatigability with bilateral tingling,
numbness and sensory disturbances. She is strict
vegetarian in diet. On examination, Pallort++t and
6.5 gm/dl, WBC 3800/cumm, Platelet count is
90000/ cumm, MCV is 1111. (a) What is your
probable diagno (b) Describe etiology, pathogenesis,
morphology and laboratory investigations of same.
fatigue, weakness facial bone deformities, slow
growth with abdominal swelling. She has history of
frequent blood transfusion since she was 3 years of
age: Laboratory findings show total RBC count 2.3
70%, HBA1 27.5% and HBA2 15 9 5%.(a) What is
your probable diagnosis? (b) Describe etiology,
pathogenesis, morphology and laboratory
investigations of same.
enumerate the steps in the investigation of a
transfusion reaction.
58.Write short notes: (three out of four) (18)
b) Define and Describe Hemophilia.
reaction.
d) Describe bleeding disorders related to defective
platelet functions.
6.Answer in two to three sentences only: (five out
a) FAB classification of Acute Leukemia.
b) Differences between Intravascular and Extra
vascular Hemolysis.
d) Enumerate various blood components,
***
Second Year MBBS Examination
II MBBS Pathology Paper 1 (New)
Time: 3 hours Max Marks: 100 Date: 06-01-2023
Instructions: 1. Answer to the points.
--- Content provided by FirstRanker.com ---
2. Figure to the right indicates marks.3. Use separate answer books for each section.
4. Draw diagrams wherever necessary.
5. Write legibly.
Section 1
--- Content provided by FirstRanker.com ---
1.Structured long answer question : (one out oftwo) (10)
a) Enumerate causes of cell injury. Describe
pathogenesis and morphology of cell injury.
b) Enlist the chemical mediators of acute
--- Content provided by FirstRanker.com ---
inflammation. Describe the role of importantmediators of acute inflammation. Write different
between acute and chronic inflammation.
2A.Applied short notes: (two out of three) (12)
a) Describe pathogenesis, Enumerate route of
--- Content provided by FirstRanker.com ---
transmission and Laboratory investigations of AIDS.b) A 55 year old lady was brought to the emergency
room unconscious. Her blood pressure was very low,
pulse was weak and rapid. Her skin was warm and
flushed. Her blood culture revealed growth of Gram
--- Content provided by FirstRanker.com ---
positive bacteria. (a) What is the possible diagnosis?(b) Describe the pathogenesis of thig condition. (c)
Describe the stages of this disorder.
c) Define Metastasis. Describe routes and
mechanism of metastasis.
--- Content provided by FirstRanker.com ---
28.Write short notes: (three out of four) (18)a) Define Obesity. Describe etiopathogenesis and
metabolic effect of obesity.
b) Define Gangrene. Describe pathophysiology of
gangrene and difference between Wet and dry
--- Content provided by FirstRanker.com ---
gangrene.d) Define and classify amyloidosis and describe
morphology of amyloid Spleen.
3.Answer in two to three sentences only: (five out
of Six) (10)
--- Content provided by FirstRanker.com ---
a) Name four paraneoplatic syndromes.b) Define Autonomy.
c) Enlist the sPectrum of autoantibodies in SLE,
d) Define metaplasia and give two examples of it.
e) Give four ,-xamples hypertrophy.
--- Content provided by FirstRanker.com ---
f) Cardinal) signs of Inflammation.Section 2
4. Structured long answer question:(one out of
two) (10)
a) Classify Anemia. Describe pathogenesis
--- Content provided by FirstRanker.com ---
hematologic features and laboratory Miegnosts ofSickle cell anemia.
b) Define chronic myeloid leukemia. Describe
etiology, clinical features and laboratory findings of
CML.
--- Content provided by FirstRanker.com ---
5A.Applied short notes: (two out of three) (12)a) 20 year female come to OPD with complain of
weakness, easy fatigability with bilateral tingling,
numbness and sensory disturbances. She is strict
vegetarian in diet. On examination, Pallort++t and
--- Content provided by FirstRanker.com ---
briefy red tongue. Complete blood count shows HB6.5 gm/dl, WBC 3800/cumm, Platelet count is
90000/ cumm, MCV is 1111. (a) What is your
probable diagno (b) Describe etiology, pathogenesis,
morphology and laboratory investigations of same.
--- Content provided by FirstRanker.com ---
b) A 1 year female come to OPD with complain offatigue, weakness facial bone deformities, slow
growth with abdominal swelling. She has history of
frequent blood transfusion since she was 3 years of
age: Laboratory findings show total RBC count 2.3
--- Content provided by FirstRanker.com ---
million/cumm, HB 6.6 gm/dl, HPLC shows HBF is70%, HBA1 27.5% and HBA2 15 9 5%.(a) What is
your probable diagnosis? (b) Describe etiology,
pathogenesis, morphology and laboratory
investigations of same.
--- Content provided by FirstRanker.com ---
c) Describe Blood Transfusion Reactions andenumerate the steps in the investigation of a
transfusion reaction.
58.Write short notes: (three out of four) (18)
b) Define and Describe Hemophilia.
--- Content provided by FirstRanker.com ---
c) Write difference between leukemia and leukamoidreaction.
d) Describe bleeding disorders related to defective
platelet functions.
6.Answer in two to three sentences only: (five out
--- Content provided by FirstRanker.com ---
of six) (10)a) FAB classification of Acute Leukemia.
b) Differences between Intravascular and Extra
vascular Hemolysis.
d) Enumerate various blood components,
--- Content provided by FirstRanker.com ---
e) Indications of Autologous blood transfusion.***