Date: 05-03-2021
GAL 2002
Second Year MBBS Examination
II MBBS Pharmacology Paper 2
Time: 2 hours Max Marks: 40

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Instructions:
1. Answer to the points.
2. Figure to the right indicates marks.
3. Use separate answer books for each section.
4. Draw diagrams wherever necessary.

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5. Write legibly.
Section 1
1. Multiple choice questions (10)
a. Primarily used to promote ovulation in
females wishing to become pregnant:(A)

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Danazol (B) Medroxyprogesterone acetate(C)
L-Norgestrel (D) Clomiphene
b. Mechanism of action of isoniazid(INH) is: (A)
Competitive inhibitor with PABA (B) Mycolic
acid synthesis inhibitor (C) Binds and inhibits

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RNA polymerase (D) Blocks protein synthesis

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c. Which is HIV protease inhibitor?(A)
Saquinavir(B) Ribavirin(C) Stavudine(D)
Rimantadine
d. The Drug associated with "Gray baby

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syndrome" which is characterized by
pallor,cyanosis, and even death is (A)
Tetracyclin (B) Chloramphenicol (C) Third-
generation cephalosporins (D)(A) & (B)
e. Bleeding from warfarin may be reversed

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by(A) Protamine sulphate(B) Enoxaparin(C)
Hirudin(D) Vitamin B
f. Which one of the following insulin
preparations exibits a relatively longer
duration of action?(A) Glulisine (B) Lispro (C)

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Detemir(D) Aspart
g. Which antimicrobial is used topical(A)
Neomycin(B) Streptokinase(C) Kanamycin(D)
Penicillin G
h. Montelukast acts by (A) Inhibiting mast cells

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(B) Inhibiting IgE antibody (C) MBB receptor
antagonism (D) Leukotriene receptor
antagonism
i. All are advantages of Azithromycin over
Erythromycin EXCEPT (A) Higher efficacy (B)

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Once daily dosing (C) Active against
Erythromycin-resistant bacteria (D) Better
gastric tolerance
j. Toxicity of Methotrexate can be overcome by

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(A) Niacin (B) Folinic acid (C) Riboflavin (D)

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Retinoic acid
Section 2
1. Write short notes on: (two out of any three)
(10)
a. Treatment of amoebiasis

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b. Treatment of typhoid fever
c. Treatment of status asthmaticus
2. Write briefly on: (four out of five) (10)
a. Suppressive prophylaxis of Malaria
b. Shared toxicities of aminoglycoside

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antibiotics
c. Beta lactamase inhibitors
d. Radioactive iodine
e. Mucolytics
3. Write short notes on: (two out of any three)

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(10)
a. Indications, contraindications and adverse
drug reactions of corticosteroids
b. Fibrinolytic drugs
c. Oral contraceptives.

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