KL 2811
Second Year MBBS Examination
II MBBS Pharmacology Paper 1
Time: 2 hours Max Marks: 40
Date: 07-04-2017

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Instructions:
1. Answer to the points.
2. Figure to the right indicates marks.
3. Use separate answer books for each section.
4. Draw diagrams wherever necessary.

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5. Write legibly.
Section 1
1. MCQ (10)
a. Which of the foilowing antimuscarinic drugs
is a selective M1-blocker? a) Scopolamine b)

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Atropine c) Homatropime d) Pirenzepine
b. Which receptor is present in bronchial
muscles ?a) Alpha-1 receptor 1 b) Beta-1
receptor 1 c) Beta-2 receptor d) Alpha-2
receptor

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c. Etbyl alcohol-a) Increases body heat loss
b)Increase body heat loss c) Decreases body

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heat loss d) Does not affects body
temperature
d. Morphine does not cause -a)Urinary retention

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b) Constipation c) Dilation of biliary duct d)
Bronchiolar constriction
e. Idiosyncratic reaction of a drug is a) Type "A"
of hypersensitivity reaction b) Type of drug
antagonism c) Unpredictable inherent

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qualitatively abnormal reaction of a drug d)
Type of reaction produced by doctor
f. Which Phenomenon occurs by combination
of drugs? a) Tachyphylaxis b) Tolerance c)
Synergism d) Dependence

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g. Affinity means-a) Combination of drug with
receptor b) Capability of a drug to produce
effect c) How a drug tightly binds with the
plasma protein? d) None of above
h. Methaemoglobinemia is an adverse effect of

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a) Ketorolac b) Indomethacin c) Aspirin d)
Paracetamol
i. 8 Which of the following is a short-acting
drug? a) Lidocaine b) Procaine ?)
Bupivacaine d) Tetracaine

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j. The symptoms of mushroom poisoning
includes following except: a) Headache and
abdominal pain b) Dryness of mouth,
hallucination, hyperpyrexia ?) Nausea,
vomiting, salivation AB Bradycardia,

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hypotension, shock

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Section 2
2. Write short notes on. (Two out of three) (10)
a. Pharmacological basis of using organic
nitrates in angina pectoris

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b. Pharmacotherapy of acute amoebic
dysentery
3. Write briefly on: (Four out of five) (10)
a. Systemic routes of drug administration
b. Mechanism of NSAIDS

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c. Cheese reaction
d. Drug Tolerance
e. Therapeutic uses of diuretics
4. Write short notes on:(Two out of three) (10)
a. Non-systemic antacids

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b. Therapeutic uses of Metronidazole.
c. Therapeutic uses of adrenaline.
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