Download MBBS Ion Selective Electrodes Lecture PPT

Download MBBS (Bachelor of Medicine and Bachelor of Surgery) Latest Ion Selective Electrodes Lecture PPT


KEY WORD AND DEFINITIONS

Electrode: A conductor through which an electrical

current enters or leaves a nonmetallic portion of a circuit.

Indicator electrode: Used in potentiometry that produces

a potential representative of the species being measured.

Reference electrode: Is an electrode at which no

appropriate current is allowed to flow and which is used

to observe or control the potential of the indicator or

working electrode, respectively.
Potentiometry: An electrochemical process where the

potential difference is measured between an indicator

electrode and reference electrode when no current is

allowed to flow in the electrochemical cell.
WORKING PRINCIPLE

Membrane potentials are caused by the permeability of

certain types of membranes to selected anions or cations.

Such membranes are used to fabricate ion-selective

electrodes that selectively interact with a single ionic

species.

The potential produced at membrane-sample solution

interface is proportional to the logarithm of the ionic

activity or concentration of the ion in question

Measurements with ISEs are simple, often rapid,

nondestructive, and applicable to a wide range of
concentrations.

The ion-selective membrane is the "heart" of an ISE

as it controls the selectivity of the electrode.

Ion-selective membranes typically consist of glass,

crystalline, polymeric materials.
Ionic-selective electrodes are widely

used clinically for the measurement of

pH, PCO2 and electrolytes in whole

blood, serum, plasma and urine.

This post was last modified on 30 November 2021