Download MBBS Male Reproductive System Lecture PPT

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TESTIS

? Lies outside body cavity in the scrotum.
? Shape-- Ovoid, length-- 5cm, diameter--

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2.5cm

? Weight --10-15gm
? Tunica albuginea--white fibrous connective

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tissue capsule.

? Tunica vasculosa--highly vascularized

connective tissue below tunica albuginea.

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? Mediastinum of testis--formed by dense

connective tissue of tunica albuginea projection

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into interior of posterior border of testis.

? Mediastinum of testis--blood vessels, nerves and

ducts of testis enter and leave.

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? Connective tissue septa extend between

mediastinum and tunica albuginea and divide it

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into 250 compartment called as lobule.

? Each lobule contains 2-3 seminiferous tubule.

? Seminiferous tubule--

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? Lined with a stratified epithelium called the

germinal epithelium

? Contains two cell types

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? Spermatogenic cells that produce sperm
? Sertoli cells that support and nourish the

developing sperm.

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? Leydig cells

--Larger in size (15?20 m)
--Polyhedral in shape
--Secrete hormone testosterone-- responsible

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for spermatogenesis and the development of

male secondary sexual characters.

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? Straight tubule (Tubuli Recti)--final portion of

seminiferous tubule.

? Rete Testis--anastomosing channel in the

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mediastinum that drain straight tubule.

? Efferent ducts--they collect sperm from rete

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testis.

? Efferent ducts consists of 12-15 coiled tube that

coalesce to form head of epididymis.

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Histology of testis
? Epididymis--

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? Efferent ducts fuse to form this, highly coiled tube.
? Parts--Head, body and tail.
? Lining epithelium-- Pseudostratified columnar.
? Tail of epididymis continuous with ductus

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deferens.

? Function-- Storage and maturation of sperm.

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Epididymis
? Ductus (vas) deferens--
? Thick muscular tube extending from tail of

epididymis to prostatic part of urethra.

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? Layers in vas deferens:--

? Mucosa--lining epithelium pseudostratified

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columnar with stereocilia.
? Muscle layer--
? Outer-- longitudinal
? Middle-- circular
? Inner-- longitudinal

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? Adventitia-- loose areolar tissue


Histology of vas deferens

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SEMINAL VESICLE

? Elongated sac like with highly convulated

irregular lumen.

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? It joins with ductus deferens form ejaculatory

duct.

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? Layers of seminal vesicle:--
? Mucosa-- Thrown into highly complex folds.
? These folds join with each other to form many

crypts and cavities.

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? Epithelium-- Pseudostratified columnar
? Muscle layer--
? Inner-- Circular ,
? Outer-- Longitudinal
? Adventitia-- Loose connective tissue.

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? Secretes-- Seminal fluid that contains

fructose and prostaglandin and constitute

about 70% of ejaculate.

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Histology of seminal vesicle
PROSTATE

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? Composed of 20-50 compound tubulo-alveolar

glands.

? Embedded in a framework of fibromuscular tissue.

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? Arranged in 3 groups
i)Mucosal
ii)Submucosal
iii)Peripheral zone.

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? Histologically the prostate is made of fibromuscular

stroma and parenchyma.

? 1)Stroma (connective tissue framework)

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i) Fibromuscular capsule? Enclosing the whole

gland and consist of collagen, elastic and smooth

muscle fibres.

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ii) Fibromuscular septa? Divide the gland into

lobule.
? 2)Parenchyma (glandular tissue)

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--Consist of large number of branching tubules with

dilated ends.

--They appears as follicles, and lined by simple

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columnar epithelium.

--The lumen may contain spherical prostatic

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concretions or corpora amylacea

? Amyloid bodies (corpora amylacea)
? Present in lumen of some gland.

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? Oval dense bodies of glycoproteins.

? Formed due to condensation of secretory

products, which may become calcified.

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? The number of corpora amylacea increase with

age.
Changes in prostate with age

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? In childhood
? Small and composed of mainly fibromuscular

stroma and rudimentary ducts.

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? At puberty
? Sudden increase in size of gland due to formation

of many follicles.

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? During 3rd decade
? Irregular epithelial infolding in the lumen of

follicle.

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? During 4th decade
? Size remains constant.
? Infolding disappear.
? Amyloid bodies appear in follicle.

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? During 5th decade
? Undergo benign hypertrophy (submucosal

gland)

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? Peripheral zone is prone to cancer.
SELF ASSESMENT

MALE REPRODUCTIVE SYSTEM
1. The epithelium lining of epididymis is

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(a) Simple columnar
(b) Transitional
(c) Stratified columnar
(d) Pseudostratified columnar
2.How many seminiferous tubules are found in

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each testis of an average man?

a. 4-6

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b. 40-60

c. 400-600

d. 4000-6000

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3.Which cells produce testosterone?

a. Leydig cells

b. Sertoli cells

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c. Sustentacular cells

d. None
4.Storage and maturation of sperm occurs in

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a. Seminiferous tubule
b. Straight tubule
c. Epididymis
d. Rete Testis
5. Corpora amylacea is seen in:

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a. Prostate
b. Seminal vesicle
c. Thymus
d. Testis
6.How many layers of smooth muscle are in the

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vas deferens?

a. 1

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b. 2

c. 3

d. 4

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7.Pair structures are all except
a) Testis
b) Vas deferens
c) Prostate
d) Seminal vesicle

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Answers

1. (d) Pseudostratified columnar
2. (c). 400-600
3. (b). Sertoli cells

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4. (c). Epididymis
5. (a). Prostate
6. (c). 3
7.(c) Prostate