Download MBBS 2nd Year 2022 March 526061 Pharmacology Paper I Mcqs MCQs Question Paper

FirstRanker.com

THE TAMIL NADU DR. M.G.R. MEDICAL UNIVERSITY

[MBBS 0322] MARCH 2022 Sub. Code :6061

--- Content provided by‍ FirstRanker.com ---

M.B.B.S. DEGREE EXAMINATION

(For the candidates admitted from the Academic Year 2019-2020 Batch onwards)

SECOND YEAR

PAPER I - PHARMACOLOGY -1

O.P. Code: 526061

--- Content provided by‌ FirstRanker.com ---

Time: 30 Minutes Maximum : 20 Marks

Answer All Questions

Choose one correct answer in the box provided in the Answer Script.

No overwriting should be done.

II1. Multiple Choice Questions: (20x1=20)

--- Content provided by FirstRanker.com ---

1. Essential drugs are
   1. Life saving drugs
   2. Drugs that meet the priority health care needs of the population
   3. Drugs that are used in medical emergencies
   4. Drugs that are listed in the pharmacopoeia of a country

--- Content provided by⁠ FirstRanker.com ---

2. The loading dose of the drug is governed by its
   1. Renal clearance
   2. Plasma half life
   3. Volume of distribution
   4. Elimination rate constant

--- Content provided by FirstRanker.com ---

3. Pseudocholinesterase differ from true cholinesterase in that
   1. It hydrolyses acetylcholine at slower rate
   2. It is more susceptible to inhibition by physostigmine
   3. It doesn't hydrolyse acetylcholine
   4. It is the only form of circulating cholinesterase

--- Content provided by​ FirstRanker.com ---

4. Bromhexine acts by
   1. Inhibiting cough centre
   2. Depolymerizing mucopolysaccharides present in sputum
   3. Irritating gastric mucosa and reflexly increasing bronchial secretion
   4. Desensitizing stretch receptors in lung

--- Content provided by FirstRanker.com ---

5. The following general anesthetic has poor muscle relaxation
   1. Ether
   2. Halothane
   3. Nitrous oxide
   4. Sevoflurane

--- Content provided by FirstRanker.com ---

6. The antiepileptic drug that is effective in manic depressive illness also is
   1. Phenobarbitone
   2. Ethosuximide
   3. Phenytoin
   4. Carbamazepine

--- Content provided by​ FirstRanker.com ---

7. The major limitation to the use of clozapine for treatment of schizophrenia is
   1. Its inability to benefit negative symptoms of schizophrenia
   2. Its potential to cause agranulocytosis
   3. It produces hyperprolactinemia
   4. High incidence of extra pyramidal symptoms

--- Content provided by FirstRanker.com ---

8. Select the most suitable antiarrhythmic drug for ventricular arrhythmia due to digoxin toxicity
   1. Lidocaine
   2. Propranolol
   3. Verapamil
   4. Quinidine

--- Content provided by⁠ FirstRanker.com ---

9. Glyceryl nitrate is administered by following routes except
   1. Intravenous
   2. Intramuscular
   3. Oral
   4. Sublingual

--- Content provided by‌ FirstRanker.com ---

10. Reversible loss of taste sensation can be a side effect of the following anti hypertensive drug
    1. Prazosin
    2. Verapamil
    3. Propranolol
    4. Captopril

--- Content provided by FirstRanker.com ---

11. The following drug is a poor inhibitor of prostaglandin synthesis in peripheral tissues but more active in brain
    1. Mefenamicacid
    2. Ketorolac
    3. Paracetamol
    4. Nimesulide

--- Content provided by‌ FirstRanker.com ---

12. Prolonged lithium therapy can cause
    1. Parkinsonism
    2. Goiter
    3. Diabetes mellitus
    4. Gout

--- Content provided by​ FirstRanker.com ---

13. Which of the following drug is a potassium channel opener?
    1. Nicorandil
    2. Hydralazine
    3. Amiloride
    4. Glibenclamide

--- Content provided by‌ FirstRanker.com ---

14. Indication of desmopressin include the following except
    1. Nephrogenic diabetes insipidus
    2. Neurogenic diabetes insipidus
    3. Bleeding due to hemophilia
    4. Bedwetting in children

--- Content provided by⁠ FirstRanker.com ---

15. The following is not a valid indication for parenteral iron therapy
    1. Inadequate response to oral iron due to patient non compliance
    2. Anemia during pregnancy
    3. Anemia in a patient with active rheumatoid arthritis
    4. Severe anemia associated with chronic bleeding

--- Content provided by⁠ FirstRanker.com ---

16. The primary mechanism by which heparin inhibits coagulation of blood is
    1. Inhibition of factor XII a and XIIl.a
    2. Activation of antithrombin TI'with inhibition of factors IX and XI
    3. Inhibition of factor Xa and-thrombin mediated conversion of fibrinogen to fibrin
    4. Direct inhibition of prothrombin to thrombin conversion

--- Content provided by​ FirstRanker.com ---

17. Select the fibrinolytic-drug that is antigenic
    1. Streptokinase
    2. Urokinase
    3. Alteplase
    4. All

--- Content provided by FirstRanker.com ---

18. Which of the following hypolipidemic drug is most effective in increasing HDL cholesterol level and lowering serum triglyceride?
    1. Cholestyramine
    2. Fenofibrate
    3. Pravastatin
    4. Nicotinic acid

--- Content provided by‌ FirstRanker.com ---

19. Tranexemic acid is used in following condition
    1. Organophosphorus compound poisoning
    2. Barbiturate poisoning
    3. Excessive bleeding due to fibrinolytic drugs
    4. Bleeding due to heparin overdose

--- Content provided by‍ FirstRanker.com ---

20. The following drug is neither analgesic nor anti-inflammatory and do not have uricosuric effect, but highly efficacious in acute gout
    1. Naproxen
    2. Colchicine
    3. Prednisolone
    4. Sulfinpyrazone

--- Content provided by FirstRanker.com ---

FirstRanker.com