PTU M.Pharm 2020 March Previous Question Papers
Total No. of Pages : 01
Total No. of Questions: 06
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M.Pharmacy(Pharmacology) (2017 & Onwards) (Sem.-1)
MODERN PHARMACEUTICAL ANALYTICAL TECHNIQUES
Subject Code: MPL-101T
M.Code: 74675
Time: 3 Hrs. Max. Marks : 75
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INSTRUCTIONS TO CANDIDATES :
- Attempt any FIVE questions out of SIX questions.
- Each question carries FIFTEEN marks.
- a) Explain the principle and applications of atomic absorption spectroscopy in drug discovery. (7)
b) Discuss various factors that affect UV spectra of a compound. (8) - a) What do you understand by the terms Spin-spin coupling, coupling constant and double resonance? Discuss various factors affecting them. (10)
b) Elaborate on applications of NMR in the field of drug discovery. (5) - a) Explain mass fragmentation with suitable examples. Discuss various rules that govern mass fragmentation. (9)
b) Discuss the principle of MALDI, APCI, and TOF. (6) - a) You have to develop an analytical method on HPLC. What are the various factors you have to keep in mind that can effect the resolution? (8)
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b) Discuss principle and applications of potentiometric analysis. (7) - a) Compare Gel and capillary electrophoresis on the basis of their principle, instrumentation and applications. (8)
b) Give the principle of HPTLC and its applications in the field of pharmacology. (4)
c) Explain the principle of Moving boundary electrophoresis and XRD. (3) - a) Give the principle, instrumentation and application of DSC in pharmaceutical industry. (8)
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b) Compare GC and UPLC on the basis of principle, sensitivity and instrumentation. (7)
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NOTE : Disclosure of Identity by writing Mobile No. or Making of passing request on any page of Answer Sheet will lead to UMC against the Student.
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