Download PTU M.Pharm 2020 March 1st Sem 74694 Advanced Pharmaceutical Analysis Question Paper

Download PTU (I.K. Gujral Punjab Technical University Jalandhar (IKGPTU) M.Pharma 2020 March (Master of Pharmacy) 1st Sem 74694 Advanced Pharmaceutical Analysis Previous Question Paper

1 | M-74694 (S31)-2391

Roll No. Total No. of Pages : 01
Total No. of Questions : 06
M.Pharmacy (Pharmaceutical Analysis) (Sem.?1)
Subject Code : MPA-102T
M.Code : 74694
Time : 3 Hrs. Max. Marks: 75
1. Attempt any FIVE questions out of SIX questions.
2. Each question carries FIFTEEN marks.

1. a) How PCR is applicable in gene regulation? Explain the working of a PCR instrument. 7
b) Explain the biological assay methods for analysis of Rabies vaccine and Heparin
Sodium IP. 8
2. a) How do you classify markers in herbal pharmaceuticals on the basis of their utility in
stability testing program? Give examples. 6
b) Explain varied types of interactions among different kinds of constituents in
phytopharmaceuticals. How these are responsible for complexity and challenges in
stability testing of such products? 9
3. What is the principle of immunoassays? Write a detailed account of various types of
immunoassays with their specific applications. 15
4. a) Acelofenac is formulated in both tablets and syrup forms. The pH of the syrup is about
6. Predict the possible degradation products of acelofenac in both the forms. In which
form it will be more stable? Support your answer with mechanistic explanations. 10
b) What are various sources of residual solvents in drugs? How their presence can prove
health hazardous? Give examples. 5
5. How an assay method is different from stability-indicating assay method (SAIM)? Explain
a selective and specific SIAM with examples. Discuss various steps involved in
development of a SIAM. 15
6. a) Classify different elemental impurities with examples. Discuss their potential sources. 5
b) Write an account on photostability testing. 5
c) Define the terms qualification and quantification limits. 5
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This post was last modified on 31 March 2020