Download SGBAU B-Pharma 2019 Summer 3rd Sem Sem III Pharmaceutical Organic Chemistry New Question Paper

FirstRanker.com
A Firstranker's choice

BP301T

--- Content provided by​ FirstRanker.com ---

Pharmaceutical Organic Chemistry - II

Time : Three Hours Max. Marks : 75

Notes:

1. All questions are compulsory.
2. Assume suitable data wherever necessary.

--- Content provided by‍ FirstRanker.com ---

3. Diagrams and chemical equations should be given wherever necessary.
4. Discuss the reaction, mechanism wherever necessary.
5. Use of pen Blue/Black ink/refill only for writing the answer book.

1. Multiple Choice questions. (20 Marks)
1. The carbon atom in benzene ring are ------------
   1. SP3 hybridized

   --- Content provided by​ FirstRanker.com ---

   2. Sp hybridized
   3. sp2 hybridized
   4. none of these
2. Characteristics reactions of aromatic compounds are initiated by ----------
   1. Electrophiles

   --- Content provided by‍ FirstRanker.com ---

   2. Nucleophiles
   3. Free radicals
   4. None of these
3. For reactions of ethylbenzene, the ethyl group is considered -----------
   1. Ortho director

   --- Content provided by‍ FirstRanker.com ---

   2. Ortho-para director
   3. Meta director
   4. Ortho-meta director
4. Benzene reacts with conc. HNO3 to give nitrobenzene in presence of --------
   1. FeCl3

   --- Content provided by⁠ FirstRanker.com ---

   2. UV light
   3. conc. H2SO4
   4. AlCl3
5. The electrophile in nitration of benzene is --------
   1. NO3-

   --- Content provided by⁠ FirstRanker.com ---

   2. NO+
   3. HNO3+
   4. NO2-
6. The hexagonal ring structure of benzene was proposed by -----------
   1. Berzelius

   --- Content provided by⁠ FirstRanker.com ---

   2. Kekule
   3. Friedel craft
   4. Bayer
7. Which of the following reagent gives picric acid when reacts with phenol ------
   1. nitric acid

   --- Content provided by FirstRanker.com ---

   2. sulfuric acid
   3. formaldehyde
   4. hydrogen
8. Aniline reacts with nitrous acid at low temperature to give ---------
   1. anitrile

   --- Content provided by⁠ FirstRanker.com ---

   2. N-nitrosamine
   3. diazonium salt
   4. anitrite salt
9. Phenyl magnesium bromide when followed by hydrolysis gives to form ----—----
   1. Phenol

   --- Content provided by‍ FirstRanker.com ---

   2. Benzoic acid
   3. Bromobenzene
   4. Acetophenone
10. Fats and oils are ----------
    1. diesters of glycerol

    --- Content provided by⁠ FirstRanker.com ---

    2. diesters of glycol
    3. monoesters of glycerol
    4. triesters of glycerol
11. Alkaline hydrolysis of fats and oils is called -------- -
    1. Fermentation

    --- Content provided by‌ FirstRanker.com ---

    2. Rancidification
    3. Saponification
    4. Hydrogenation
12. which of the following cycloalkanes have highest ring strain ----------
    1. Cyclopropane

    --- Content provided by‌ FirstRanker.com ---

    2. Cyclobutane
    3. Cyclopentane
    4. Cyclohexane
13. Enzyme responsible for hydrolysis of fat is ---------
    1. Reductase

    --- Content provided by‍ FirstRanker.com ---

    2. Aconitase
    3. Lipase
    4. Kinase
14. The degree of unsaturation fat can be determined by means of its ----------
    1. Iodine number

    --- Content provided by‍ FirstRanker.com ---

    2. Saponification number
    3. Acetyl number
    4. Ester number
15. For electrophilic substitution reaction, carboxyl group in aromatic acid is -------
    1. Ortho-directing

    --- Content provided by FirstRanker.com ---

    2. Para-directing
    3. Meta-directing
    4. both (a) and (c)
16. Acyl chlorides are made by reacting aromatic acids with ----------
    1. PCl3

    --- Content provided by FirstRanker.com ---

    2. PCl5
    3. SOCl2
    4. All of above
17. Hofmann’s degradation reaction is used for the synthesis of ------
    1. Secondary aromatic amine

    --- Content provided by​ FirstRanker.com ---

    2. Primary aromatic amine
    3. tertiary aromatic amine
    4. none of above
18. Sulphonation of Phenol at room temperature gives ---==---==--
    1. para-isomer

    --- Content provided by‌ FirstRanker.com ---

    2. ortho-isomer
    3. meta-isomer
    4. both (a) and (b)
19. Which of the following is most acidic ----------
    1. benzyl alcohol

    --- Content provided by‌ FirstRanker.com ---

    2. cyclohexanol
    3. phenol
    4. o-nitrophenol
20. An aromatic molecule will -==-avee--
    1. Cyclic and planar

    --- Content provided by‌ FirstRanker.com ---

    2. have (4n +2) p electrons
    3. have p cloud above and below the plane of molecule
    4. all of above
2. Short answer questions (answer any two). (2 x 10 = 20 Marks)

--- Content provided by⁠ FirstRanker.com ---

1. What are fats and Oils? How we can check their quality?
2. Explain characteristics reactions of benzene
3. Explain the chemistry of Naphthalene.
3. Short answer questions (answer any seven). (7 x 5 = 35 Marks)
1. What are phenols? How are they prepared?

--- Content provided by⁠ FirstRanker.com ---

2. Write the various reactions of fats and oils.
3. Write a note on aryl diazonium salts.
4. Write the methods of preparation of benzoic acid.
5. What are cycloalkanes? Describe Baeyer’s strain theory.
6. Explain the effect of electron donating and withdrawing groups on electrophilic aromatic substitution reactions with example.

--- Content provided by‍ FirstRanker.com ---

7. Write a note on aromaticity of benzene.
8. Write the reactions of phenols.
9. Explain factors affecting acidity of aromatic carboxylic acids.

FirstRanker.com

--- Content provided by⁠ FirstRanker.com ---