Download SGBAU B-Pharma 2019 Summer 3rd Sem Sem III Pharmaceutical Organic Chemistry New Question Paper

Download SGBAU (Sant Gadge Baba Amravati university) B.Pharma 2019 Summer (Bachelor of Pharmacy) 3rd Sem Sem III Pharmaceutical Organic Chemistry New Previous Question Paper

B. Pharm. 11nd Year Third Semester (New)
35381 : Pharmaceutical Organic Chemistry - [I
BP 301 T 1
P. Pages: 3 IIIIIHIIINW AW - 2344
Time : Thrtc Hours . o s 9 s a Max. Marks : 75
Notes : 1. All questions are compulsory.
2. Assume suitable data wherever necessary.
3. Diagrams and chemical equations should be given wherever necessary.
4. Discuss the reaction, mechanism wherever necessary.
5. Use of pen Blue/Black ink/re?ll only for writing the answer book.
1. Multiple Choice questions. 20
i) The carbon atom in benzene ring are ------------
a) SP3 hybridized b) Sp hybridized
c) SP2 hybridized d) none of these
ii) Characteristics reactions of aromatic compounds are initiated b} ---------
a) Electrophiles b) Nucleophiles
c) Free radicals d) None of these
iii) For reactions of cthylbenzene, the ethyl group is considered --------
a) Ortho director b) Ortho-para director
~c) . Meta director d) Ortho-meta director
iv) Benzene reacts with cone. HNO3 to give nitrobenzene in presence of ~-----?---
a) FeCl3 b) UV light
0) conc. HZSO4 d) AlCl3
v) 'lhe electrophile in nitration of benzene is --------
8) N02? b) NO+
c) HN02+ d) No;+
vi) The hexagonal ring structure of benzene was proposed by -----------
a) Berzelius b) ? Kekule
c) Friedel craft d) Bayer
vii) Which of the following reagent gives picric acid when reacts with phenol -----
a) nitric acid b) sulfuric acid
c) formaldehyde d) hydrogen
viii) Aniline reacts with nitrous acid at low temperature to give ---------
a) a niln'le b) N-nitrosamine
c) a diazonium salt d) a nitrite salt
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ix) Phenyl magnesium bromide reacts with C02 followed by acid hydrolysis to
form ---------
a) Phenol b) Benzoic acid
c) Bromobenzenc d) Acetophcnonc
X) Fats and oils are ----------
a) diesters of glycerol b) diestcrs of glycol
c) monoesters of glycerol d) triesters of glycerol
xi) Alkaline hydrolysis of fats and oils is called ????? ~-
21) F ermentation b) Rancidi?cation
c) Saponi?cation d) Hydrogenation
xii) which of the following cycloalkzmes have highest ring strain --------?-
a) Cyclopropane b) C yclobutane
c) Cyclopemanc d) Cyclohexane
xiii) Enzyme responsible for hydrol) sis of fat is ---------
a) Reduclasc b) Aconilasc
c) Lipase d) Kinasc
xiv) The degree of unsaniralion fat can be determined by means of its ----------
a) Iodine number b) Saponi?cation number
c) Acetyl numbcr d) Ester number
xv: For elcctmphilic substitution reaction, carboxyl group in aromatic acid is -------
a?) Ortho-directing b) Pura-directing
c) Meta-directing d) both (a) and (c)
xvi) Acy] chlorides are made by reacting aromatic acids with --------
a) PCI3 b) PC15
c) SOC] 2 d) All of above
xvii)Hofmann?s degradation reaction is used for the synthesis of -?-----
a) Secondary aromatic amine
b) Primary aromatic amine
c) tertiary aromatic amine
d) none: of above
xviii) Sulphonation of Phenol at room temperature gives -----------
a) para-isomer b) ortho-isomer
c) meta-isomer d) both (a) and (b)
xix) Which of the following is most acidic ----------
a) benzyl alcohol b) cyclohexanol
c) phenol d) o-nitrophenol
n) An aromatic molecule will ----------
3) Cyclic and planar
b) have (4n +2) n electrons
c) have n cloud above and below the plane of molecule
d) all of above
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k)

Long answer questions answer any two. 20
i) What are fats and oils? How we can check their quality?
ii) Explain characteristics reactions of benzene
iii) Explain the chemistry of Naphthalene.
Short answer questions (answer any seven). 35
i) What are phenols? How are they prepared?
ii) Write the various reactions of fats and oils.
iii) Write a note on aryl diazonium salts.
iv) Write the methods of preparation of benzoic acid.
v) What are cycloalkanes? Describe Baeyer?s strain theory.
vi) Explain the effect of electron donating and withdrawing groups on electrophilic
aromatic substitution reactions with example.
vii) Write a note on aromaticity ol?benzene.
viii) Write the reactions of phenols.
ix) Explain factors affecting acidity of aromatic carboxylic acids.
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