RGUHS M.Pharm 2nd Year Last 10 Years 2011-2021 Question Papers || Rajiv Gandhi University of Health Sciences
Draw neat, labeled diagrams wherever necessary.
LONG ESSAY (Answer any Three) 3 X 10 = 30 Marks
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- Explain one compartmental open model with extra vascular route of administration along with various pharmacokinetic parameters.
- Explain the various mechanisms of drug absorption.
- Describe the in vitro drug dissolution testing models. Explain their merits and limitations.
- Explain the causes of non-linearity in pharmacokinetics of drugs. Add a note on estimation of Vmax and Km.
SHORT ESSAY (Answer any Nine) 9 X 5 = 45 Marks
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- Explain pH partition hypothesis and its limitations.
- Explain the protocol for bioequivalence studies.
- Discuss Pharmacokinetic drug interactions.
- Write the objectives of bioavailability studies. Enlist the methods for measurement of bioavailability. Explain method using plasma concentration data.
- Define and classify compartment models. Discuss briefly the significance and limitation of compartment modeling.
- Write the applications of Pharmacokinetics in novel drug delivery systems.
- Explain the influence of gastric emptying and intestinal transit time on absorption of drugs.
- Explain in vivo methods for determining absorption of drugs.
- Discuss Pharmacokinetics and Pharmacodynamics of biotechnology drugs.
- Explain biological factors affecting drug absorption.
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