Download RGUHS (Rajiv Gandhi University of Health Sciences) MBBS (Bachelor of Medicine and Bachelor of Surgery) 2nd Year (Second Year) 2023 Feb 1028 Pharmacology Paper I Rs 4 Previous Question Paper
Rajiv Gandhi University of Health Sciences, Karnataka
MBBS Phase ? II (CBME) Degree Examination - 08-Feb-2023
Time: Three Hours
Max. Marks: 100 Marks
PHARMACOLOGY ? PAPER I (RS-4)
Q.P. CODE: 1028
(QP contains two pages)
Your answers should be specific to the questions asked
Draw neat, labeled diagrams wherever necessary
LONG ESSAYS
2 x 10 = 20 Marks
1.
A 42 years old lady was brought to casualty with symptoms of irritation of eyes, excessive
salivation and lacrimation, blurring of vision, breathlessness, involuntary defecation and
urination. Based on these symptoms physician made a diagnosis of acute
organophosphorous compound poisoning
a) Outline the management of Organophosphorous Poisoning
b) Discuss the uses of reversible anticholinesterases?
2.
a) Classify opioid analgesics with suitable examples
b) Discuss the central nervous system actions of Morphine
c) Enumerate four contraindications for the use of morphine
SHORT ESSAYS
8 x 5 = 40 Marks
3. 1. A 40 year old patient complains of sleep disturbances since 2 weeks. He was prescribed a
Benzodiazepine by the physician. Describe the mechanism of action and adverse effects of
Diazepam
4. 2. Therapeutic uses of Beta-blockers
5. 3. Explain Drug synergism with suitable examples
6.
Advantages and disadvantages of Intravenous route of administration of drugs
7.
Mention four second generation antihistaminics. Enumerate their advantages over firstirst
generation antihistaminics
8.
Methods of prolonging drug action
9.
Mechanism of action, therapeutic uses and adverse effect of Proton Pump inhibitors
10. A 28 year old lady presents with complains of episodic breathlessness accompanied by
wheezing. A diagnosis of Bronchial asthma was made by the attending physician
a) Mention three different group of drugs giving one example for each used in the
management of Bronchial asthma
b) Describe the mechanism of action of any one group
SHORT ANSWERS
10 x 3 = 30 Marks
11. What is therapeutic drug monitoring (TDM)? Mention two drugs that require TDM.
12. Name three centrally acting skeletal muscle relaxants
13. Enumerate three techniques of local anaesthesia with one indication for each
14. Rationale of using Glycopyrrolate for preanaesthetic medication
15. Rationale of using Colchicine in acute gout
16. Name three newer antiepileptic drugs
17. Mention three drugs used as expectorants
18. Mention three uses of Dimercaprol
19. Mention three rational fixed dose combination of drugs
20. Rationale of using Ondansetron in cancer chemotherapy induced vomiting
Page 1 of 2
QP CODE : 1028
Rajiv Gandhi University of Health Sciences, Karnataka
Multiple Choice Questions
10 x 1 = 10 Marks
21 i) The feature of a highly plasma protein bound drug is
A. Biologically very active
B. Rapidly excreted
C. Long acting
D. Sh
ort acting
21 ii
) A 35 year old lady presents with drooping of eyelid, muscle weakness of arms and legs
and fatigue. The physician made a diagnosis of the myasthenia gravis. The drug useful
in this condition is
A. Donepezil
B. Atropine
C. Neostigmine
D. Pra
lidoxime
21 ii
i) A 42 year old woman suffering from trigeminal neuralgia consults a physician for
treatment. Which of the following drug is useful in this patient?
A. Carbamazepine
B. Ethosuximide
C. Felbamate
D. Phen
obarbitone
21 iv)
Which of the following drug is used as nasal decongestant?
A. Nimesulide
B. Naphazoline
C. Norepinephrine
D. Nore
thindrone
21 v)
One cause for Tachyphylaxis is
A. Up regulation of receptors
B. Increased neurotransmitter concentration
C. Sensitization of receptors
D. De
sensitization of receptors
22 i) Antiemetic associated with extrapyramidal side effects is
A. Metoclopramide
B. Ondansetron
C. Aprepitant
D. De
xamethasone
22
ii) Lignocaine acts as a local anaesthetic agent by blocking the neuronal
A. Sodium channels
B. Potassium channels
C. Calcium channels
D. Chlori
de channels
22 iii) Which of the following is used as Antitussive drug?
A. Etomidate
B. Dextromethorphan
C. Bromhexine
D. Ace
tylcysteine
22 iv)
Which of the following antihistaminic drug is highly sedative?
A. Cetrizine
B. Ranitidine
C. Loratidine
D. Prom
ethazine
22 v)
Which of the following chelating agents is used in treatment of Copper poisoning
A. Naloxone
B. d-penicillamine
C. Dexamethasone
D. N acetylcysteine
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This post was last modified on 02 December 2024