Download RGUHS (Rajiv Gandhi University of Health Sciences) MBBS (Bachelor of Medicine and Bachelor of Surgery) 2nd Year (Second Year) 2024 Jan 1026 Pathology Paper I Rs 4 Previous Question Paper
Rajiv Gandhi University of Health Sciences, Karnataka
MBBS Phase ? II (CBME) Degree Examination - 30-Jan-2024
Time: Three Hours
Max. Marks: 100 Marks
PATHOLOGY ? PAPER I (RS-4)
Q.P. CODE: 1026
(QP contains two pages)
Your answers should be specific to the questions asked
Draw neat, labeled diagrams wherever necessary
LONG ESSAYS
2 x 10 = 20 Marks
1.
10 year old male presented with pain abdomen, fever and vomiting of one day duration.
On examination there is tenderness over Mcburney's point. Ultrasound examination of the
abdomen showed evidence of dilated appendix.
a) What type of inflammation is seen in this condition?
b) Discuss the cellular events occurring in this condition
c) List the chemical mediators that facilitate the cellular events
2.
13 year old male has sudden onset of severe abdominal pain and cramping accompanied
by chest pain, non productive cough, pain in the bones of the hand and fever. Physical
examination revealed that his temperature is 39C and pulse rate is 110/min. He has
diffuse abdominal tenderness and spleenomegaly. Lab studies show haematocrit of 18%
and peripheral smear showed sickle shaped cells. X ray chest showed bilateral pulmonary
infiltrates
a) Discuss the pathogenesis of the sudden onset symptoms in the child
b) Discuss the laboratory investigations relevant to the history provided
SHORT ESSAYS
8 x 5 = 40 Marks
3. 1. Microscopic variants of Hodgkins Lymphoma.
4. 2. Enumerate the steps in the investigations of the transfusion reaction.
5. 3. Define necrosis. Discuss various types of necrosis with examples.
6.
Paraneoplastic syndrome.
7.
Type I hypersensitivity.
8.
Chemical carcinogenesis.
9.
Etiopathogenesis of Septic shock.
10. Define hypertrophy. Discuss the types of hypertrophy with their mechanism.
SHORT ANSWERS
10 x 3 = 30 Marks
11. Draw labelled diagram of fatty liver.
12. List any three tumour suppressor genes.
13. Stains for amyloidosis.
14. Packed cell volume.
15. Define granuloma and draw a neat diagram.
16. Differences between transudate and exudate.
17. Exfoliative cytology.
18. Fate of thrombus.
19. Draw peripheral smear picture of Megaloblastic anaemia.
20. Causes of Thrombocytopenia.
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QP CODE : 1026
Rajiv Gandhi University of Health Sciences, Karnataka
Multiple Choice Questions
10 x 1 = 10 Marks
21 i) All are chemical mediators of acute inflammation EXCEPT
A. Histamine
B. Prostaglandin
C. Leukotrienes
D. Progesterone
21 ii
) 50 year old male presents with breathlessness and weight loss. Imaging revealed
nodular lesion in the left lung lower lobe. Biopsy shows an adenocarcinoma. Which of the
following is the likely mutation associated with this condition?
A. EGFR mutation
B. PTEN mutation
C. BCL2 mutation
D. APC
mutation
21 ii
i) Ghon's complex comprises of which one of the following
A. Hilar lymphadenopathy
B. Apical fibrocavitatory lesion
C. Miliary lesions across bilateral lungs
D. Progre
ssive primary lesions
21 iv)
Down's syndrome is due to
A. Trisomy 22
B. Trisomy 21
C. Trisomy 18
D. Trisomy
20
21 v)
63 year old male hypertensive develops paralysis of the right side of the body. Which of
the following patterns of tissue injury is likely to be present in the brain after 4-5 days?
A. Fat necrosis
B. Caseous necrosis
C. Coagulated necrosis
D. Liquef
active necrosis
22 i) Acute promeylocytic leukemia characteristically shows presences of Auer rods in the
blast. Which of the following stains highlight these Auer rods
A. Verhoff stain
B. Myeloperoxidase
C. PAS
D. Gl
ial fibrillary acidic protein
22
ii) 70 year old male presented with worsening heart failure. Echocardiogram showed
cardiomegaly with four chamber dilatation. Which type of amyloid is likely to be present
in the heart
A. SAA
B. Transthyretin
C. AL
D. Beta2 microglobulin
22 iii) ESR is markedly raised in
A. Multiple myeloma
B. Malaria
C. Acute myeloblastic leukemia
D. Haem
ophilia
22 iv)
Howell Jolly bodies are seen in
A. Myeloblasts
B. Lymphoblasts
C. Megaloblasts
D. Sickle
cell
22 v)
Neutrophilia is typically seen in
A. Acute bacterial infections
B. Typhoid
C. Malaria
D. Infectious mononucleosis
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This post was last modified on 02 December 2024