Download OU (Osmania University) Pharm D (Doctor of Pharmacy) V Sem (5th Semester) 2020 6202 PB Clinical Pharmacokinetics And Pharmacotherapeutic Drug Monitoring Previous Question Paper
Code No. 6202 / PB
FACULTY OF PHARMACY
Pharm D (3 ?YDC) II ?Year (Instant) (Post Baccalaureate) Examination, February 2020
Subject: Clinical Pharmacokinetics & Pharmacotherapeutic Drug Monitoring
Time: 3 Hrs Max.Marks: 70
Note: Answer all questions from Part ? A. Any Five questions from Part ? B.
PART ? A (10x2 = 20 Marks)
1 Write abt determination of dose and dosing interval.
2 Write the TDM for phenytoin sodium.
3 Explain abt innulin clearance.
4 Write a note on enzyme inhibition with examples.
5 Add a note on Biliary Excretion.
6 Give a brief accnt on dosage adjustment in uremic patients
7 Brief abt pharmacogenetics and its applications.
8 Write a brief note on dosing with feedback.
9 What is the role of pharmacist in clinical pharmacokinetics?
10 Write the significance of population pharmacokinetics.
PART ? B (5x10 = 50 Marks)
11 Describe the following:
a) Pharmacokinetic correlation in drug therapy. [5]
b) Bayesian theory [5]
12 Explain in detail abt the role of g enetic polymorphism in drug metabolism and target
with examples. [10]
13 a) Explain varis diseases where TDM is applicable. [4]
b) Dosage variability with respect to genetics, disease and age. [6]
14 Write a note on drug dosing in elderly and pediatric patients. [10]
15 Add a note on:
a) Induction of drug metabolism. [5]
b) Dosage adjustment in hepatic disease. [5]
16 Explain varis pharmacokinetic drug -drug interactions with suitable examples. [10]
17 Explain abt the following:
a) GFR and creatinine clearance. [5]
b) Adaptive method with feedback. [5]
18 Write in brief abt clinical pharmacokinetics. [10]
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This post was last modified on 04 March 2020