Download GTU B.Pharma 2020 Winter 4th Sem BP403TP Physical Pharmaceutics Ii Question Paper

Download GTU (Gujarat Technological University Ahmedabad) B.Pharma (Bachelor of Pharmacy) 2020 Winter 4th Sem BP403TP Physical Pharmaceutics Ii Previous Question Paper

Seat No.: _____ Enrollment No. _____________

GUJARAT TECHNOLOGICAL UNIVERSITY
B Pharm. SEMESTER-IV EXAMINATION ?WINTER -2020
Subject Code: BP403TP
Date: 11/02/2021
Subject Name: Physical Pharmaceutics-II
Time: 02:30PM TO 04:30PM
Total Marks: 54
Instructions:


1. Attempt any THREE questions from Q-1 to Q-6.
2. Q.7 is compulsory to attempt.
3. Make suitable assumptions wherever necessary.
4. Figures to the right indicate full marks.

Q.1 (a) Differentiate Lyophilic colloids and Lyophobic colloids. Discuss association 06
colloids.

(b) Explain the concept of DLVO theory along with energy curve and how this 05
theory is applied in stabilizing the colloidal dispersion.

(c) Enlist different properties of colloids. Explain kinetic properties.
05



Q.2 (a) Enumerate different methods commonly used for measurement of particle size
06
determination. Describe optical microscopy method.

(b) Classify the methods used for determination of surface area. Explain air
05
permeability method with diagram.

(c) Define and explain: Angle of repose and Carr's Index with their
05
pharmacopoeial specification.



Q.3 (a) Explain sedimentation parameters of suspension in detail.
06

(b) Enlist the physical instability markers of emulsion and explain any two.
05

(c) Discuss various mechanism of emulsifying agents.
05



Q.4 (a) Discuss accelerated stability testing in expiration dating of pharmaceutical
06
dosage forms.

(b) Derive the equation of Half life for zero order and first order kinetics.
05

(c) Write about chemical factors influencing the chemical degradation of
05
pharmaceutical product.



Q.5 (a) Explain the plastic and pseudoplastic flow curves with example.
06

(b) Define: Kinematic viscosity, Fluidity, Bulges, Rheopexy and Poise.
05

(c) Explain cup and bob viscometer with diagram.
05



Q. 6 (a) Discuss porosity and packing arrangement of powder with application of
06
micromeritics.

(b) Describe different types of emulsion.
05

(c) Define thixotropy. Comment on thixotropy and antithixotropy.
05



Q.7 (a) Enlist the different type of densities of powder. Write the experimental method
06
for the determination of any one of them.
OR

(a) Define suspension. Write a note on factors affecting stability of suspension.
06
OR

(a) Write the principle and working of Ostwald viscometer.
06
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