Download GTU B.Pharma 2020 Winter 8th Sem 2280003 Pharmaceutical Chemistry X (Medicinal Chemistry Iii) Question Paper

Download GTU (Gujarat Technological University Ahmedabad) B.Pharma (Bachelor of Pharmacy) 2020 Winter 8th Sem 2280003 Pharmaceutical Chemistry X (Medicinal Chemistry Iii) Previous Question Paper

Seat No.: _____ Enrolment No. _____________
GUJARAT TECHNOLOGICAL UNIVERSITY
B.PHARM - SEMESTER? VIII ? EXAMINATION ? WINTER -2020
Subject Code: 2280003
Date: 06/01/2021
Subject Name: Pharmaceutical Chemistry-X (Medicinal Chemistry-III)
Time: 02:00PM TO 04:00PM
Total Marks: 54
Instructions:


1. Attempt any THREE questions from Q-1 to Q-6.
2. Q.7 is compulsory to attempt.
3. Make suitable assumptions wherever necessary.
4. Figures to the right indicate full marks.

Q.1 (a) Define and classify Diuretic Agents. Discuss the SAR among Progestins and
06
Androgens.

(b) Give the method of synthesis of (i) Lignocaine (ii) Atenolol
05

(c) Discuss the SAR among HMG CoA Reductase inhibitors.
05



Q.2 (a) What is Diabetes? Classify antidiabetics with examples and give their
06
mechanism of action.

(b) Give SAR of ACE inhibitors.
05

(c) Give the method of synthesis of (i) Acetazolamide (ii) Captopril
05



Q.3 (a) Give the method of synthesis of
06
(i) Warfarin (ii) Metformin (iii) Carbimazole.

(b) Discuss the SAR among
05
(i) Thiazide Diuretics (ii) 5 ? Sulfamoyl Benzoic acid derivatives.

(c) Discuss the SAR among
05
(i) Estrogens (ii) Dihydropyridnes



Q.4 (a) Discuss the SAR among Cardiac glycosides.
06

(b) Write informative note on Anti platelet Agents.
05

(c) Discuss detail about plasma expanders.
05



Q.5 (a) Explain in detail the nomenclature and stereochemistry of Steroidal
06
Compounds.

(b) Write down notes on Coagulants and Anticoagulants.
05

(c) Write short notes on Thrombolytic agents.
05



Q. 6 (a) Give the method of synthesis of
06
(i) Clofibrate (ii) Ethacrinic acid (iii) Glimipride

(b) Define and classify Hypoglycemic Agents.
05

(c) Write short notes on Thrombolytic agents.
05



Q.7 (a) What are the causes of hypertension? Write a note on B-blockers.
06
OR

(a) What is obesity? Write a note on antiobesity drugs.
06
OR

(a) Write detail note on Cardio tonic Agents.
06
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