Download GTU B.Pharma 2020 Winter 5th Sem BP501TT Medicinal Chemistry Ii Question Paper

Download GTU (Gujarat Technological University Ahmedabad) B.Pharma (Bachelor of Pharmacy) 2020 Winter 5th Sem BP501TT Medicinal Chemistry Ii Previous Question Paper

Seat No.: _____ Enrolment No. _____________
GUJARAT TECHNOLOGICAL UNIVERSITY
B.Ph. - SEMESTER?V ? EXAMINATION ? WINTER-2020
Subject Code:BP501TT
Date: 02/01/2021
Subject Name: Medicinal Chemistry II
Time: 10:30AM TO 12:30PM
Total Marks: 54
Instructions:


1. Attempt any THREE questions from Q-1 to Q-6.
2. Q.7 is compulsory to attempt.
3. Make suitable assumptions wherever necessary.
4. Figures to the right indicate full marks.

Q.1 (a)
Enlist various histamine receptors. Discuss neurochemistry of histamine.
06

(b)
Short note on oral contraceptives.
05

(c) Write synthesis of following
05
i)
i) Promethazine hydrochloride ii) Cimetidine



Q.2 (a)
Discuss in detail about proton pump inhibitors along with its mechanism of
06
action.

(b)
Short note on H2 receptor antagonist.
05

(c) What do you mean by Diuretics? Classify and give the synthesis of Furesemide.
05



Q.3 (a) Short note on Antiarithmetic agents
06

(b) Write short notes on coagulants and anticoagulants.
05

(c) Write Synthesis of following
05
i) Nitroglycerin ii) Methyldopa



Q.4 (a)
SAR of local anaesthetic.
06

(b) Write Synthesis of following
05
i) Tolbutamide ii) Benzocaine

(c)
Define and classify Antianginal agents with the synthesis of Isosobide dinitrate.
05



Q.5 (a)
Discuss the various factors which are affecting on blood coagulation and write
06
a note on Warfarin.

(b)
Define antihypertensive agents with its classification and write a
05
note on calcium channel blockers.

(c) Write Synthesis of following
05
i) Chlorthiazide ii) Acetazolamide



Q. 6 (a)
Write short notes on stereochemistry of steroids.
06

(b)
Short note on testesteron.
05

(c)
Give detail account on various corticosteroids.
05



Q.7 (a)
What is Diabetes? Classify antidiabetics with examples and give their
06
mechanism of action.
OR

(a)
Write a note on antithyroid drugs.
06
OR


(a)
What is obesity? Write a note on antiobesity drugs.
06



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