Download GTU B.Pharma 2020 Summer 3rd Sem BP302TP Physical Pharmaceutics I Question Paper

Download GTU (Gujarat Technological University Ahmedabad) B.Pharma (Bachelor of Pharmacy) 2020 Summer 3rd Sem BP302TP Physical Pharmaceutics I Previous Question Paper

Seat No.: _____ Enrolment No. _____________
GUJARAT TECHNOLOGICAL UNIVERSITY
B.Pharm SEMESTER? III EXAMINATION ? SUMMER -2020
Subject Code:BP302TP
Date: 27-10-2020
Subject Name: Physical Pharmaceutics I
Time: 2:30 PM TO 5:30 PM
Total Marks: 80
Instructions:


1. Attempt any five questions.
2. Make suitable assumptions wherever necessary.
3. Figures to the right indicate full marks.

Q.1 (a) Explain about partially miscible liquid by taking example of Phenol Water
06
system.

(b) Write the mechanism of solute-solvent interaction.
05

(c) Explain the factor affecting solubility of drug.
05



Q.2 (a) Enlist the methods for determination of surface and Interfacial tension. Explain
06
capillary rise method in detail.

(b) Define surface tension. Write its unit, Discuss the HLB scale in detail.
05

(c) Write in brief about detergency and give application of surfactants.
05



Q.3 (a) Write a note on organic molecular complexes.
06

(b) Give the application of complexes in detail.
05

(c) Classify types of complex. Explain Inclusion complex in detail.
05



Q.4 (a) Write a note on Liquid crystals.
06

(b) Explain in brief about glassy state and polymorphism.
05

(c) What is dielectric constant and dipole moment? Write its application.
05



Q.5 (a) Write a note on Pharmaceutical buffer.
06

(b) Explain buffer equation and buffer capacity.
05

(c) Enlist the adjustment methods of tonicity and explain freezing point depression
05
method.



Q. 6 (a) What is Adsorption Isotherm? Describe different types of Adsorption Isotherm.
06
Discuss Freundlich Isotherm.

(b) Explain liquefaction of gases and methods of achieving liquefaction. Give
05
application of this phenomenon in pharmacy.

(c) Define- Solubility, Rauolt's law, critical solution temperature, diffusion,
05
solvation.



Q.7 (a) What is spreading co-efficient ? Derive its equation.
06

(b) Explain in brief about Eutectic Mixture with Phase diagram.
05

(c) Explain in brief about drug protein binding.
05
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