Download GTU B.Pharma 2019 Winter 5th Sem BP501TT Medicinal Chemistry Ii Question Paper

Download GTU (Gujarat Technological University Ahmedabad) B.Pharma (Bachelor of Pharmacy) 2019 Winter 5th Sem BP501TT Medicinal Chemistry Ii Previous Question Paper

Seat No.: _____ Enrolment No. _____________
GUJARAT TECHNOLOGICAL UNIVERSITY
B.Ph.- SEMESTER?V ? EXAMINATION ? WINTER -2019
Subject Code: BP501TT
Date: 15/11/2019
Subject Name: Medicinal Chemistry-II
Time: 02:30PM TO 05:30PM
Total Marks: 80

Instructions:


1. Attempt any five questions.
2. Make suitable assumptions wherever necessary.
3. Figures to the right indicate full marks.

Q.1
(a) Define and classify oral hypoglycemic agents.
06

(b) Explain the SAR of local anesthetic agents.
05

(c)
Give detail note on thyroid hormones and write a note on anti-thyroid drugs.
05



Q.2
(a) Write a note on nomenclature and stereochemistry of steroids.
06

(b) Discuss coagulants and anticoagulants.
05

(c)
Give detail note on oral contraceptives.
05



Q.3
(a) Define and classify Antiarrhythmic drugs. Explain mode of action in each class.
06

(b) Write a note on proton pump inhibitors.
05

(c)
Write a note on drugs used in congestive heart failure.
05



Q.4
(a) Give structure and uses of (i) Diltiazem (ii) Verapamil (iii) Clofibrate
06

(b) Explain types of diabetes and write a note on various insulin preparations.
05

(c)
Write a short note on ACE inhibitors.
05



Q.5
(a) What are anti-histaminic? How they act? Classify them with examples.
06

(b) Write a note on HMG Co-A reductase inhibitors.
05

(c)
Write a note on H2-antagonists.
05



Q. 6
(a) Define and Classify Antihypertensive agents with examples.
06

(b) Give Synthesis of (i) Diphenhydramine hydrochloride (ii) Furosemide
05

(c)
Write a note on potassium sparing diuretics and thiazide diuretics.
05



Q.7
(a) Write detail classification and short mechanism of action of anticancer agents
06

(b) Give Synthesis of (i) Cimetidine (ii) Tolbutamide
05

(c)
Write short note on corticosteroids.
05
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