Download GTU B.Pharma 2018 Winter 3rd Sem 230004 Pharmaceutical Analysis I Question Paper

Download GTU (Gujarat Technological University Ahmedabad) B.Pharma (Bachelor of Pharmacy) 2018 Winter 3rd Sem 230004 Pharmaceutical Analysis I Previous Question Paper

Seat No.: ________ Enrolment No.______________

GUJARAT TECHNOLOGICAL UNIVERSITY
B.PHARM ? SEMESTER ? 3- EXAMINATION ?WINTER - 2018

Subject Code:230004
Date: 12/12/2018
Subject Name: Pharmaceutical Analysis - I
Time:10:30 AM TO 01:30 PM
Total Marks: 80
Instructions:

1. Attempt any five questions.

2. Make Suitable assumptions wherever necessary.

3. Figures to the right indicate full marks.

Q.1 (a) What is analytical method validation? Enlist validation parameter. Discuss any
06
two parameters in detail.

(b) Define hydrolysis and Derive equation for finding pH of aqueous solution of
05
salt of strong acid and weak base.

(c) Describe sampling techniques.
05



Q.2 (a) What is error? Write types of errors and how they minimized.
06

(b) Differentiate between QA and QC.
05

(c) Give a detailed account of Oxygen combustion flask method.
05



Q.3 (a) Explain the terms: (i) Co-precipitation (ii) Post precipitation (iii) Solubility
06
product

(b) Discuss in detail about Diazotization nitrite titration.
05

(c) Write a note on Karl-Fischer titration.
05



Q.4 (a) Write a short note on Common ion effect and ionic product of water.
06

(b) Write a note on pM indicators.
05

(c) What is gravimetric analysis? Enlist the steps involved in gravimetric analysis.
05



Q.5 (a) Explain redox indicators in detail.
06

(b) What is buffer? Derive Henderson-Hasselbach equation.
05

(c) Explain Kjeldahl method for determination of nitrogen.
05



Q. 6 (a) Write a brief note on types of non aqueous solvents and leveling and
06
differentiating effect of solvent.

(b) Give the difference between followings with suitable example
05
(1) Iodometric titration and Iodimetric titration
(2) Masking agent and Demasking agent

(c) Explain law of mass action.
05



Q.7 (a) Comments: (1) Nitrobenzene is used in Volhard's method
06
(2) KMnO4 is not a primary standard compound.
(3) Electrolyte solution is used for wash precipitate.

(b) Write explanatory note on: Continuous extraction.
05

(c) Discuss in detail about Fajan's method.
05
***************

---