Download GTU B.Pharma 2018 Winter 6th Sem 2260002 Pharmaceutical Microbiology And Biotechnology Ii Question Paper

Download GTU (Gujarat Technological University Ahmedabad) B.Pharma (Bachelor of Pharmacy) 2018 Winter 6th Sem 2260002 Pharmaceutical Microbiology And Biotechnology Ii Previous Question Paper

Seat No.: ________ Enrolment No.______________

GUJARAT TECHNOLOGICAL UNIVERSITY
B.PHARM ? SEMESTER ? 6- EXAMINATION ?WINTER - 2018

Subject Code:2260002
Date: 27/11/2018
Subject Name: Pharmaceutical Microbiology & Biotechnology - II
Time:02:30 PM TO 05:30 PM
Total Marks: 80
Instructions:

1. Attempt any five questions.

2. Make Suitable assumptions wherever necessary.

3. Figures to the right indicate full marks.

Q.1 (a) Explain the different parts of a Fermentor with their functions with a labeled
06
diagram.

(b) Write a note on components of a fermentation media.
05

(c) Explain in brief the production of streptomycin by fermentation process
05



Q.2 (a) Describe the primary defensive mechanisms of the body in brief.
06

(b) Explain the process of making BCG vaccine with a flow diagram
05

(c) Define and classify Immunity with suitable examples
05



Q.3 (a) Describe the production of monoclonal antibodies by hybridoma technology
06

(b) Describe techniques of protoplast fusion.
05

(c) Describe in brief mechanisms of Gene Transfer
05



Q.4 (a) Discuss the principle and method of microbiological assay of antibiotics by cup
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plate method

(b) Differentiate between: ( i) Active and passive Immunity (ii) Vaccine and Sera
05

(c) Describe the structure of an antibody. Classify types of antibodies along with
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their function.



Q.5 (a) Describe the process of recombinant DNA technology with a suitable diagram.
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What are restriction enzymes?

(b) Describe the production of Humulin( Human Insulin) by recombinant DNA
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technology

(c) Write a note on Vectors used in recombinant DNA technology
05



Q. 6 (a) Define Mutation. Classify and define types of mutation.
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(b) Discuss the process of collection and storage of whole human blood
05

(c) Discuss causes of mutation.
05



Q.7 (a) Explain the principle and method of sterility testing. Which Pharmaceuticals
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are required to be tested for sterility?

(b) Write a note on Dried Human Plasma.
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(c) Describe in brief Antigen antibody reactions
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